摘要
新型冠状病毒引起的全球卫生危机仍在继续,而且病毒不断发生变异,传播速度逐渐变快。既往研究表明,维生素D可以在调节免疫、抑制炎症、干预肾素-血管紧张素系统等方面发挥作用,而且低维生素D水平与新型冠状病毒肺炎(COVID-19)严重程度以及死亡率之间存在联系。因此维生素D在减轻COVID-19病情严重程度上具有一定价值。但是目前的临床研究还没有明确维生素D用于广泛人群预防重症新冠肺炎的最佳补充剂量,这仍需要进一步的基础和临床试验来探索。
Recently,COVID-19 is still considered to be a common health issue around the world and the virus continues to mutate to a faster form.Recent studies have shown that vitamin D is of great importance in reducing the severity of COVID-19.Vitamin D can modulate immunity,suppress inflammation and intervene in the renin-angiotensin system.And low vitamin D level is associated with COVID-19 severity and mortality.However,current clinical studies have not yet identified the optimal dose of vitamin D for the prevention of severe COVID-19;a lot of basic and clinical trials are needed to explore the optimal dose for severe COVID-19 prevention.
作者
马思远
刘秉昆
石芳彬
邹文玉
Ma Siyuan;Liu Bingkun;Shi Fangbin;Zou Wenyu(Weifang Medical University,Weifang 261000,China;Department of Cardiology,Yidu Central Hospital of Weifang,Weifang 261000,China;Medical Record Management Center,Affiliated Hospital of Qingdao University,Qingdao 266000,China;Cheeloo College of Medicine,Shandong University,Jinan 250000,China)
出处
《国际内分泌代谢杂志》
2022年第3期179-183,共5页
International Journal of Endocrinology and Metabolism
