摘要
目的:观察盆炎方联合针刺治疗气滞血瘀型盆腔炎性疾病后遗症(SPID)的临床疗效。方法:纳入108例气滞血瘀型SPID患者,随机分为指南组、中药组、针药组,每组各36例。指南组患者给予膈下逐瘀汤口服,中药组患者给予盆炎方口服,针药组患者在中药组治疗基础上结合针刺治疗。治疗周期为3个月经周期。评价3组患者的临床疗效;治疗前后,采用视觉模拟评分法(VAS)评价患者的主观疼痛程度,检测患者的白介素-10(IL-10)和肿瘤坏死因子-α(TNF-α)水平。结果:(1)治疗后,指南组、中药组、针药组的临床总有效率分别为61.11%、72.22%、86.11%,3组比较差异有统计学意义(P<0.05),针药组的疗效优于中药组、指南组(P<0.05),中药组的疗效优于指南组(P<0.05)。(2)治疗后,3组患者的VAS评分均显著降低(P<0.05),且针药组的评分低于中药组、指南组(P<0.05),中药组的评分低于指南组(P<0.05)。(3)治疗后,3组患者的血清TNF-α水平均降低、IL-10水平均升高(P<0.05),且针药组患者的IL-10水平高于指南组、中药组(P<0.05),中药组患者的IL-10水平高于指南组(P<0.05),针药组患者的TNF-α水平低于指南组、中药组(P<0.05)。结论:盆炎方联合针刺治疗气滞血瘀型SPID,能有效改善患者的疼痛症状,调节相关炎性指标水平,值得临床推广。
Objective:To observe the clinical effects of Penyan Formula combined with acupuncture on sequelae of pelvic inflammatory disease(SPID)with qi stagnation and blood stasis type.Methods:A total of 108 SPID patients with qi stagnation and blood stasis type were included and randomly divided into the guideline group,traditional Chinese medicine group and acupuncture combined with traditional Chinese medicine group,36 cases in each group. The patients in the guideline group were orally treated with Gexia Zhuyu Decoction,the patients in traditional Chinese medicine group were orally treated with Penyan Formula,and the patients in the acupuncture combined with traditional Chinese medicine group were treated with acupuncture based on the treatment of traditional Chinese medicine group. The treatment course was three menstrual cycles. The clinical effects of the three groups were evaluated. Before and after treatment,the subjective pain of the patients was evaluated by visual analogue scale(VAS),and the levels of interleukin(IL)-10 and tumor necrosis factor-α(TNF-α)were detected.Results:(1)After treatment,the clinical total effective rates of the guideline group,traditional Chinese medicine group and acupuncture combined with traditional Chinese medicine group were 61.11%,72.22% and 86.11% respectively,with a statistical difference among the three groups(P<0.05). The effect of the acupuncture combined with traditional Chinese medicine group was better than that of traditional Chinese medicine group and the guideline group(P<0.05),and the effect of traditional Chinese medicine group was better than that of the guideline group(P<0.05).(2) After treatment,the VAS scores of the three groups were significantly decreased(P<0.05),and the score of the acupuncture combined with traditional Chinese medicine group was lower than that of traditional Chinese medicine group and the guideline group(P<0.05),the score of traditional Chinese medicine group was lower than that of the guideline group(P<0.05).(3) After treatment,the levels o
作者
徐维娜
陈双佳
顾申枫
陈逸嘉
XU Weina;CHEN Shuangjia;GU Shenfeng;CHEN Yijia(Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;Zhoujiadu Community Health Services Center,Pudong New Area,Shanghai 200126,China;Pujin Community Health Services Center,Shanghai 201112,China;Jing'an District Central Hospital,Shanghai 200040,China;Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200032,China)
出处
《上海中医药大学学报》
CAS
2022年第2期26-30,共5页
Academic Journal of Shanghai University of Traditional Chinese Medicine
基金
上海市闵行区科委自然基金资助项目(2020MHZ099)
上海中医药大学附属龙华医院爱建捐赠基金项目(Y1713)
上海中医药大学第20期课程建设项目(SHUTCM2021KC115)。
关键词
盆腔炎性疾病后遗症
盆炎方
针药结合
白介素-10
肿瘤坏死因子-Α
sequelae of pelvic inflammatory disease
Penyan Formula
acupuncture combined with medicine
interleukin-10
tumor necrosis factor-α
