摘要
目的:开展肠易激综合征(Irritable bowel syndrome,IBS)的文献研究,探讨IBS患者的体质分布规律和特点。方法:通过中国知网(CNKI)、万方、维普(VIP)及中国生物医学数据库(CBM)在线检索IBS相关文献,筛选体质辨识及流行病学研究文献,提取体质分布等信息建立数据库,分析IBS及其不同亚型患者体质分布情况,并与中国正常人群体质分布数据进行比较以分析前者的体质分布特点。结果:纳入12篇文献,共2043例病例,其中男性962例,女性1081例。IBS疾病最常见的体质为阳虚质(22.2%)、气郁质(21.5%)、气虚质(13.4%)及湿热质(12.2%),其中IBS-D患者阳虚质占比更为明显,为25.5%,而IBS-C患者气郁质和湿热质占比更多,分别为30.9%和18.1%,且阴虚质(11.4%)占比较IBS-D显著增加。IBS-D女性患者气郁质(21.1%)占比高于男性(16.1%),而男性痰湿质(13.0%)占比高于女性(7.4%)。与正常人群体质相比,IBS患者阳虚质和气郁质占比显著增加,平和质和血瘀质占比明显降低。结论:IBS患者的体质分布与正常人群有一定的差异,阳虚质、气郁质、气虚质和湿热质是其主要的体质类型,不同的亚型和性别对其体质分布有一定影响。
Objective:Literature study on irritable bowel syndrome(IBS)was carried out to explore the characteristics of constitution distribution of patients with IBS.Methods:The literatures of constitution identification and epidemiological research were searched and filtrated online from CNKI,Wanfang,VIP and CBM,and the information database of constitution distribution of IBS was established.Analyzed the constitution distribution of IBS and its different subtypes,and compared the constitution distribution data with the normal population in China to analyze the constitution distribution characteristics of the former.Results:12 references were included,with a total of 2043 patients including 962 males and1081 females.The most common constitutions of IBS were yang-deficiency(22.2%),qi-stagnation(21.5%),qi-deficiency(13.4%)and damp-heat(12.2%),among which the proportion of yang-deficiency(25.5%)was more obvious in patients with IBS-D,while the proportion of qi-stagnation(30.9%)and damp-heat(18.1%)in patients with IBS-C was more significant.The proportion of yin deficiency(11.4%)was much in IBS-C than IBS-D.The proportion of qi-stagnation(21.1%)in female patients with IBS-D was higher than that in male patients(16.1%),while the proportion of phlegm-dampness(13.0%)in male patients was higher than that in female patients(7.4%).Compared with the normal population,the proportion of yin-deficiency and qi-stagnation in IBS patients increased significantly,while the proportion of peaceful and blood-stasis in IBS patients decreased significantly.Conclusion:The physical distribution of IBS patients is different from that of the normal population.Yang deficiency,qi stagnation,qi deficiency and dampness and heat are the main types of IBS,and different subtypes and gender have a certain impact on the physical distribution.
作者
殷锦锦
秦书敏
吴皓萌
郑欢
饶珂寒
黄绍刚
YIN Jinjin;QIN Shumin;WU Haomeng;ZHENG Huan;RAO Kehan;HUANG Shaogang
出处
《新中医》
CAS
2022年第11期20-24,共5页
New Chinese Medicine
基金
国家自然科学基金项目(81904148)
中国中医药循证医学中心中医消化领域优势病种(肠易激综合征)专科专病循证能力提升项目(2019XZZX-XH002)
广东省普通高校青年创新人才项目(2019KQNCX023)
广东省医学科学技术研究基金项目(A2020181,A2020161)
广州中医药大学学科研究重点项目(XK-2019027)
广东省中医药局中医药科研项目(20192024)。
关键词
肠易激综合征
体质
数据挖掘
Irritable bowel syndrome
Constitution
Data mining
