摘要
目的 分析妇科微创手术患者使用丙泊酚麻醉的临床效果。方法 100例行妇科微创手术患者,根据麻醉药物不同分为对照组和干预组,每组50例。对照组患者使用七氟醚麻醉,干预组患者使用丙泊酚麻醉。比较两组患者不同时间[建立气腹前(T1)、气腹10 min(T2)、气腹30 min(T3)、术毕(T4)]生理指标[平均动脉压(MAP)、心率(HR)]、生化指标[皮质醇(Cor)、血糖(Glu)]及治疗情况(意识消失时间、手术时间、术后意识恢复时间、用药剂量)。结果 T1、T2、T3、T4时,两组患者MAP、HR比较差异无统计学意义(P>0.05)。T1时,两组患者Cor、Glu比较差异无统计学意义(P>0.05);T2、T3、T4时,干预组患者Cor、Glu低于对照组,差异具有统计学意义(P<0.05)。干预组患者意识消失时间(60.25±4.25)s、手术时间(50.52±4.51)min、术后意识恢复时间(4.58±0.32)min短于对照组的(66.15±4.85)s、(54.35±4.85)min、(6.91±0.61)min,用药剂量(128.35±12.35)mg少于对照组的(164.75±16.54)mg,差异具有统计学意义(P<0.05)。结论 妇科微创手术患者使用丙泊酚麻醉能够降低对生化指标的影响,降低钙离子内流,降低交感循环神经活性,降低手术期间患者机体应激反应,临床应用价值显著。
Objective To analyze the clinical effect of propofol anesthesia on patients undergoing minimally invasive gynecological surgery. Methods A total of 100 patients undergoing minimally invasive gynecological surgery were divided into control group and intervention group according to different anesthetic drugs, with 50 cases in each group. Patients in the control group were anesthetized with sevoflurane, and patients in the intervention group were anesthetized with propofol. Both groups were compared in terms of physiological indexes [mean arterial pressure(MAP), heart rate(HR)], biochemical indicators [cortisol(Cor), blood glucose(Glu)] at different time points [before the establishment of pneumoperitoneum(T1), 10 min of pneumoperitoneum(T2), 30 min of pneumoperitoneum(T3), and after surgery(T4)], and treatment conditions(consciousness disappear time, operation time, postoperative consciousness recovery time, and drug dosage). Results At T1, T2,T3, and T4, there was no statistically significant difference in MAP and HR between the two groups(P>0.05). At T1, there was no statistically significant difference in Cor and Glu between the two groups(P>0.05);at T2, T3,and T4, the Cor and Glu in the intervention group were lower than those in the control group, and the difference was statistically significant(P<0.05). The consciousness disappearance time(60.25±4.25) s, operation time(50.52±4.51) min, and postoperative consciousness recovery time(4.58±0.32) min of the intervention group were shorter than(66.15±4.85) s,(54.35±4.85) min, and(6.91±0.61) min of the control group, and the drug dosage(128.35±12.35) mg was less than(164.75±16.54) mg of the control group. All the differences were statistically significant(P<0.05). Conclusion The use of propofol anesthesia in patients with minimally invasive gynecological surgery can reduce the impact on biochemical indicators, reduce the influx of calcium ions, lower the activity of sympathetic circulation, and reduce the stress response of patients during surgery, which is
作者
李晓梅
LI Xiao-mei(Department of Anesthesiology,Meishan Women and Children's Hospital,West China Second Hospital,Sichuan University,Meishan 620010,China)
出处
《中国实用医药》
2022年第11期127-129,共3页
China Practical Medicine
关键词
丙泊酚
麻醉
妇科微创手术
应用效果
Propofol
Anesthesia
Minimally invasive gynecological surgery
Application effect
