摘要
目的 探讨结直肠癌患者采取腹腔镜、结肠镜联合手术治疗的临床疗效与安全性。方法 选取2018年6月—2021年6月该院接受手术治疗的96例结直肠癌患者为研究对象,根据单双号方式分为观察组(单号,48例)与对照组(双号,48例),对照组单纯接受腹腔镜手术治疗,观察组实施腹腔镜、结肠镜联合手术治疗,记录两组患者临床手术指标及术后恢复情况,监测对比两组患者治疗前后Th1、Th2、Th1/Th2及血清应激指标变化,观察统计两组患者术后并发症总发生率。结果 两组患者手术时长、术中出血量指标比较,差异无统计学意义(P>0.05),观察组患者术后恢复用时均明显短于对照组,差异有统计学意义(P<0.05)。术后观察组患者Th1(10.45±1.53)%、Th1/Th2(2.12±0.22)高于对照组,Th2(4.93±0.35)%低于对照组,差异有统计学意义(t=4.660、18.720、29.655,P<0.05)。观察组术后血清应激指标水平低于对照组,差异有统计学意义(P<0.05)。观察组患者术后并发症总发生率为4.17%,低于对照组,差异有统计学意义(χ^(2)=7.207,P<0.05)。结论 结直肠癌患者通过采取腹腔镜、结肠镜联合手术治疗方式能够有效减轻手术对患者造成的应激反应。
Objective To investigate the clinical efficacy and safety of laparoscopic and colonoscopy combined surgery for colorectal cancer patients.MethodsSelected 96 colorectal cancer patients undergoing surgical treatment in the hospital from June 2018 to June 2021 were selected as the research subjiects.According to odd and even numbers,they were divided into observation group(odd number,48 cases) and control group(even number,48 cases).The control group received laparoscopic surgery alone,and the observation group received laparoscopic and colonoscopy combined surgery.The clinical operation indexes and postoperative recovery of the two groups of patients were recorded,and the changes of Th1,Th2,Th1/Th2 and serum stress indexes were monitored and compared in the two groups before and after treatment.The total incidence of postoperative complications in two groups was observed.ResultsThere was no statistically significant difference in the operation time and intraoperative blood loss between the two groups(P>0.05).The postoperative recovery time of the observation group was significantly shorter than that of the control group,the difference was statistically significant(P<0.05).After operation,the Th1(10.45±1.53)% and Th1/Th2(2.12±0.22) of the observation group were higher than those of the control group,and the Th2(4.93±0.35)%was lower than those of the control group,the difference was statistically significant(t=4.660,18.720,29.655,P<0.05).The level results of serum stress indexes in the observation group were lower than those of the control group,the difference was statistically significant(P<0.05).The total incidence of postoperative complications in the observation group was 4.17%,lower than that in the control group,the difference was statistically significant(χ~2=7.207,P<0.05).ConclusionThe combination of laparoscopy and colonoscopy in patients with colorectal cancer can effectively reduce the stress response caused by surgery to patients,and it is recommended to promote it.
作者
闵建平
潘海涛
MIN Jianping;PAN Haitao(Department of Hepatobiliary and Gastrointestinal Surgery,Juye County People's Hospital of Heze,Juye,Shandong Province,274900 China)
出处
《系统医学》
2022年第10期88-91,共4页
Systems Medicine
关键词
腹腔镜手术
结肠镜手术
结直肠癌
应激指标
安全性
Laparoscopic surgery
Colonoscopy surgery
Colorectal cancer
Stress index
Safety
