摘要
目的:探索大蒜、洋葱的热性物质基础。方法:采用噻唑蓝(MTT)比色法考察大蒜、洋葱所含的12种硫醚类化合物对离体培养的MCF-7细胞生长增殖的影响,以确定其寒热属性。结果:在一定的浓度范围内,12种硫醚类化合物对体外培养的MCF-7细胞的生长增殖均表现为促进作用。结论:硫醚类化合物药性属热,是大蒜、洋葱显示热性的物质基础之一。
Objective: The thermal material basis of garlic and onion was explored Method: The effects of 12thioether compounds contained in garlic and onion on the growth and proliferation of MCF-7 cells in vitro were investigated by thiazolyl blue(MTT) colorimetric method to determine their cold and heat properties. Result: In a certain concentration range, the 12 thioether compounds showed promoting effect on the growth and proliferation of MCF-7 cells cultured in vitro. Conclusion: The medicinal properties of thioether compounds are hot, which is one of the material bases for garlic and onion to show hot properties.
作者
程薇薇
刘建利
史敏
毕芳芳
张露
袁悦
CHENG Weiwei;LIU Jianli;SHI Min;BI Fangfang;ZHANG Lu;YUAN Yue(School of Medicine,Xi’an Peihua University,Xi’an 710125,China;School of Life Sciences,Northwest University,Xi’an 710069,China)
出处
《食品安全导刊》
2022年第17期48-50,共3页
China Food Safety Magazine
基金
西安培华学院2021年校级科研项目“基于细胞中药学理论从蛋白表达角度探索中药寒热药性的作用靶点”(PHKT2123)
西安培华学院2021年大学生创新创业训练计划项目“双歧杆菌联合左卡尼汀对菌群失调腹泻模型大鼠肠道菌群的影响”(PHDC2021065)
陕西省教育厅2020年度突发公共卫生安全专项科学研究计划“黄芩素对小鼠急性肺炎的干预效果及其药理调节机制研究”(20JG023)。
