摘要
目的分析重症支原体肺炎患儿开展支气管镜肺泡灌洗治疗的作用。方法选择2020年1月至2021年12月河南科技大学第一附属医院收治的62例重症支原体肺炎患儿。采用随机数字表法分成常规组(31例)与试验组(31例),将常规治疗应用于常规组患儿中,将常规治疗及支气管镜肺泡灌洗应用于试验组患儿中。对两组病患各时期肺功能指标水平、各时期C反应蛋白(CRP)水平、治疗效果、不良反应及退热、咳嗽缓解、肺部湿啰音消失、住院时间进行比较。结果治疗一周后同组组内最大呼气中期流量、用力肺活量、第一秒用力呼气容积均高于治疗前,试验组患儿最大呼气中期流量、用力肺活量、第一秒用力呼气容积均高于常规组,差异有统计学意义(P<0.05)。治疗一周后同组组内CRP水平低于治疗前,试验组患儿低于常规组,差异有统计学意义(P<0.05)。试验组与常规组患儿治疗有效率依次是93.55%、74.20%,差异有统计学意义(P<0.05)。试验组与常规组患儿不良反应出现率依次是9.68%、6.45%,差异无统计学意义(P>0.05)。试验组患儿退热、咳嗽缓解、肺部湿啰音消失和住院时间均短于常规组,差异有统计学意义(P<0.05)。结论重症支原体肺炎患儿开展支气管镜肺泡灌洗治疗,能够提高心肺功能,降低炎性因子水平,缩短临床症状恢复时间,强化治疗效果,同时不良反应少,安全性良好。
Objective To analyze the effect of bronchoalveolar alveolar lavage in children with severe mycoplasma pneumonia.Methods A total of 62 children with severe mycoplasma pneumonia in the First Affiliated Hospital of Henan University of science and technology were selected as the subjects of the study from January 2020 to December 2021.The patients were divided into the routine group(31 cases)and the experimental group(31 cases)according to the random number table.The routine treatment was applied to the children in the routine group,and the routine treatment and bronchoalveolar alveolar lavage were applied to the children in the experimental group.The lung function index level,C-reactive protein(CRP)level,treatment effect,adverse reactions,disappearance time of fever,cough,lung moist rales and hospitalization time were compared in each group.Results After one week of treatment,the maximum mid expiratory flow,forced vital capacity and forced expiratory volume in the first second in the same group were higher than those before treatment.The maximum mid expiratory flow,forced vital capacity and forced expiratory volume in the first second in the experimental group were higher than those in the routine group(P<0.05).After one week of treatment,the CRP level in the same group was lower than that before treatment,and that in the experimental group was lower than that in the routine group,the difference was statistically significant(P<0.05).The effective rates of the experimental group and the routine group were 93.55%and 74.20%respectively,with significant difference(P<0.05).The incidence of adverse reactions in the experimental group and the routine group were 9.68%and 6.45%respectively,with no significant difference(P>0.05).The fever abatement,cough remission,disappearance of lung moist rales and hospitalization time in the experimental group were shorter than those in the routine group,and the difference was statistically significant(P<0.05).Conclusion Bronchoalveolar alveolar lavage in children with severe mycoplasma p
作者
赵彩红
ZHAO Caihong(Department of Pediatrics,The First Affiliated Hospital of Henan University of science and technology,Luoyang Henan 471000,China)
出处
《临床研究》
2022年第7期8-11,共4页
Clinical Research
关键词
肺功能
炎性因子
支原体肺炎
重症
肺泡灌洗
支气管镜
lung function
inflammatory factors
mycoplasma pneumonia
severe
alveolar lavage
bronchoscope
