摘要
目的研究牙周基础治疗在慢性牙周炎合并2型糖尿病患者中的应用效果。方法选取2020年3月至2021年3月三明市中西医结合医院收治的80例慢性牙周炎合并2型糖尿病患者作为研究对象,按照抽签法分为对照组(40例)与干预组(40例)。对照组口服常规药物奥硝唑片与头孢克洛进行治疗,干预组在对照组的基础上采用牙周基础治疗。比较两组的牙周治疗指标[牙龈沟出血指数(SBI)与牙周探诊深度(PD)]、炎症因子指标[肿瘤坏死因子-α(TNF-α)与高敏C反应蛋白(hs-CRP)]与血糖指标(空腹血糖与餐后2 h血糖水平)。结果干预组治疗后的SBI与PD低于对照组,差异有统计学意义(P<0.05);干预组治疗后的TNF-α水平与hs-CRP水平低于对照组,差异有统计学意义(P<0.05);干预组治疗后的空腹血糖水平与餐后2 h血糖水平低于对照组,差异有统计学意义(P<0.05)。结论慢性牙周炎合并2型糖尿病患者应用牙周基础治疗的效果显著,能有效缓解、消除牙周疾病,降低炎症因子水平,还能降低其血糖水平,促进其血糖控制效果,改善其身心健康与生活质量,值得推广应用。
Objective To study the application effect of periodontal foundation therapy in patients with chronic periodontitis and type 2 diabetes mellitus.Methods From March 2020 to 2021,80 patients with chronic periodontitis complicated with type 2 diabetes mellitus treated into Sanming Integrated Medicine Hospital from March 2020 to March 2021 were selected as the research objects.They were divided into the control group(40 cases)and the intervention group(40 cases)according to ballot methods.The control group was treated with Ornidazole Tablets and Cefaclor,while the intervention group was treated with periodontal basic therapy on the basis of the control group.The periodontal treatment indexes(sulcus bleeding index[SBI]and periodontal probing depth[PD])and the inflammatory factor index(tumor necrosis factor-α[TNF-α]and high sensitive C-reactive protein[hs-CRP])and blood glucose index(fasting blood glucose and 2-hour postprandial blood glucose level)were compared between the two groups.Results The levels of SBI and PD in the intervention group were lower than those in the control group,the differences were statistically significant(P<0.05).The levels of TNF-αand hs-CRP in the intervention group were lower than those in the control group,the differences were statistically significant(P<0.05).The fasting blood glucose level and 2-hour postprandial blood glucose level in the intervention group were lower than those in the control group,the differences were statistically significant(P<0.05).Conclusion The application effect of periodontal basic therapy is effective in patients with chronic periodontitis and type 2 diabetes mellitus.It can effectively relieve and eliminate periodontal diseases,reduce inflammatory factors,and reduce blood glucose level,promote blood glucose control,improve physical and mental health and quality of life,and is worthy of popularization and application.
作者
李贝贝
LI Beibei(Department of Stomatology,Sanming Integrated Medicine Hospital,Fujian Province,Sanming 365000,China)
出处
《中国当代医药》
CAS
2022年第18期103-106,共4页
China Modern Medicine
关键词
牙周基础治疗
慢性牙周炎
2型糖尿病
血糖水平
Periodontal basic therapy
Chronic periodontitis
Type 2 diabetes mellitus
Blood glucose level
