摘要
目的探讨精细化临床护理路径(CNP)在抗病毒药物治疗慢性乙型肝炎(CHB)患者中的应用价值。方法选择2019年1月至2021年1月新乡医学院第三附属医院收治的122例CHB患者为研究对象,采用随机数字表法将患者分为观察组和对照组,每组61例。所有患者给予抗病毒药物治疗,观察组患者在抗病毒药物治疗过程中给予精细化CNP干预,对照组患者给予常规护理干预,2组患者均干预6个月。干预前后,采用Mishel疾病不确定感量表(MUIS-A)评估患者的疾病不确定感,采用Zung焦虑量表(SAS)和抑郁自评量表(SDS)评估患者的心理状态,采用一般自我效能量表(GSES)评估患者的自我效能,采用Morisky药物依从性量表(MMAS-8)评估患者的服药依从性,采用慢性肝病问卷(CLDQ)评估患者的生活质量。结果干预前2组患者MUIS-A评分比较差异无统计学意义(P>0.05),2组患者干预后MUIS-A评分显著低于干预前(P<0.05),且干预后观察组患者MUIS-A评分显著低于对照组(P<0.05)。干预前2组患者SAS、SDS评分比较差异无统计学意义(P>0.05),2组患者干预后SAS、SDS评分显著低于干预前(P<0.05),且干预后观察组患者SAS、SDS评分显著低于对照组(P<0.05)。干预前2组患者GSES评分比较差异无统计学意义(P>0.05),2组患者干预后GSES评分显著高于干预前(P<0.05),且干预后观察组患者GSES评分显著高于对照组(P<0.05)。干预前2组患者MMAS-8评分、服药依从性比较差异无统计学意义(P>0.05),2组患者干预后MMAS-8评分、服药依从性显著高于干预前(P<0.05);干预后,观察组患者MMAS-8评分、服药依从性显著高于对照组(P<0.05)。干预前2组患者CLDQ评分比较差异无统计学意义(P>0.05),2组患者干预后CLDQ评分显著高于干预前(P<0.05)。干预后,2组患者系统症状、腹部不适得分比较差异无统计学意义(P>0.05),但观察组患者疲劳、活动能力、焦虑、情感功能得分及CLDQ总分显著高于对照组(
Objective To investigate the application value of refined clinical nursing pathway(CNP)in the antiviral therapy of patients with chronic hepatitis B(CHB).Methods A total of 122 CHB patients admitted to the Third Affiliated Hospital of Xinxiang Medical University from January 2019 to January 2021 were selected as the research subjects,and the patients were divided into the observation group and control group by random number table method,with 61 cases in each group.All patients were treated with antiviral drugs,and the patients in the observation group were treated with refined CNP intervention during the course of antiviral drug treatment,while the patients in the control group were treated with routine nursing intervention.All patients in both groups were intervened for 6 months.Before and after the intervention,the disease uncertainty of the patients was evaluated by Mishel′s uncertainty in illness scale-adult(MUIS-A),the psychological state of the patients was assessed by Zung self-rating anxiety scale(SAS)and self-rating depression scale(SDS),the self-efficacy of the patients was assessed by the general self-efficacy scale(GSES),the medication adherence was assessed by Morisky medication adherence scale(MMAS-8),and the patients′quality of life was assessed by the chronic liver disease questionnaire(CLDQ).Results There was no significant difference in the MUIS-A score of patients between the two groups before intervention(P>0.05).The MUIS-A scores of patients in the two groups after intervention were significantly lower than those before intervention(P<0.05).The MUIS-A scores of patients in the observation group were significantly lower than those in the control group(P<0.05).There was no significant difference in the SAS and SDS scores of patients between the two groups before intervention(P>0.05).The SAS and SDS scores of patients in the two groups after intervention were significantly lower than those before intervention(P<0.05).The SAS and SDS scores of patients in the observation group were significan
作者
冯新霞
赵巍峰
FENG Xinxia;ZHAO Weifeng(Department of Infectious Diseases,the Third Affiliated Hospital of Xinxiang Medical University,Xinxiang 453003,Henan Province,China)
出处
《新乡医学院学报》
CAS
2022年第6期583-588,共6页
Journal of Xinxiang Medical University
基金
国家科技部科技计划重大专项课题(编号:2017zx10203202-005)。
