摘要
疲劳是帕金森病患者最常见、最具致残性的非运动症状之一,对其生活质量有重要影响。由于既往缺乏对帕金森病伴发疲劳严格统一的定义和明确的量化标准,可能导致不同的研究结论。2016年关于帕金森病伴发疲劳定义和诊断建议的专家共识发表后,这一领域的规范研究得到部分补充,但临床医师对其识别及干预仍显不足。文中通过对帕金森病伴发疲劳的定义和分类、流行病学和影响因素、临床评定、治疗管理措施等进行综述,为临床帕金森病伴发疲劳患者的识别和管理提供参考。
Fatigue is one of the most common and disabling symptoms of Parkinson′s disease(PD),which has an important impact on the quality of life.Due to the lack of a strict and unified definition and classification of PD-related fatigue,as well as a clear quantitative standard,clinical studies on fatigue in PD have drawn different conclusions,making fatigue research challenging.Normative studies in this area have been complemented by the publication of the 2016 expert consensus on diagnostic criteria for PD associated fatigue.In this paper,the incidence,influencing factors,clinical evaluation measures and treatment of PD-related fatigue were reviewed to provide the latest information for clinical identification and management of PD-related fatigue patients.
作者
李利
范振毅
李达
严旺
Li Li;Fan Zhenyi;Li Da;Yan Wang(Department of Neurology,Hwa Mei Hospital,University of Chinese Academy of Sciences,Ningbo 315010,China)
出处
《中华神经科杂志》
CAS
CSCD
北大核心
2022年第6期665-670,共6页
Chinese Journal of Neurology
基金
华美研究基金(2021HMKY18)。
关键词
帕金森病
疲劳
识别
治疗和管理
Parkinson disease
Fatigue
Recognition
Management
