摘要
目的探究经尿道前列腺等离子剜除术对前列腺增生症患者的治疗效果及对该类患者控尿能力、血清睾酮水平及前列腺特异抗原水平的生理影响。方法选取长治医学院附属和济医院泌尿外科2019年6月至2021年3月107例良性前列腺增生症患者,根据随机数字表法分组,对照组53例予经尿道前列腺切除术(TURP)治疗,观察组54例予经尿道前列腺等离子剜除术(PKEP)治疗,对比两组患者围手术期指标、控尿能力、血清水平及术后并发症。结果观察组手术时间低于对照组,差异有统计学意义(P<0.05);观察组最大尿流率(Qmax)水平高于对照组,残余尿量、国际前列腺症状评分(IPSS评分)水平低于对照组,差异有统计学意义(P<0.05);观察组血清睾酮、前列腺特异抗原水平低于对照组,差异有统计学意义(P<0.05);两组患者术后出血、膀胱刺激征、尿道狭窄和包膜穿孔发生率比较,差异无统计学意义(P>0.05)。结论TURP术与PKEP术对治疗良性前列腺增生均有一定的临床效果,但PKEP术的手术时间较短,有助于提高患者预后生理指标,降低血清睾酮水平及前列腺特异抗原水平,提高临床预后效果。
Objective To investigate the efficacy of transurethral plasma kinetic enucleation of prostate(PKEP)on patients with prostatic hyperplasia and the physiological effects on urinary continence ability,serum testosterone(T)level and pros tate-specific antigen(P SA)level in thes e patients.Methods A total of 107 patients with benign prostatic hyperplasia(BPH)in the Department of Urinary Surgery in Heji Hospital Affiliated to Changzhi Medical College from June 2019 to March 2021 were selected as study subjects.They were divided into the control group(n=53)and the observation group(n=54)according to the random number table m ethod,with the control group treated with trans urethral resection of pros tate(TURP)and the observation group tr eated with tr ansurethral PKEP.The two groups were com pared in term s of perioperative indexes,urinary continence ability,serum levels and postoperative complications.Results The surgical duration of the observation group was shorter than that of the control group,with statistically significant difference(P<0.05).The maximum urinary flow rate(Qmax)was higher and the residual urine volume and International Prostate Symptom Score(IPSS)were lower in the observation group than those in the control group,with statistically significant differences(P<0.05).The levels of serum T and P SA in the obs ervation group were lower than those in the control group,with statistically significant differences(P<0.05).There were no statistically significant differences between the two groups in the incidences of postoperative bleeding,bladder irritation signs,urethral stricture and capsule perforation(P>0.05).Conclusion Both the TURP and PKEP have certain clinical effects for BPH,but PKEP has a shorter surgical duration,and is helpful to improve the prognostic physiological indicators of patients,reduce the levels of serum T and PSA,as well as improve the clinical prognosis.
作者
岳永俊
尚鹏飞
赵波
YUE Yongjun;SHANG Pengfei;ZHAO Bo(Department of Urinary Surgery,Heji Hospital Affiliated to Changzhi Medical College,Shanxi,Changzhi 046000,China)
出处
《中国医药科学》
2022年第10期128-131,共4页
China Medicine And Pharmacy
关键词
前列腺增生
控尿能力
血清睾酮
术后并发症
经尿道前列腺等离子剜除术
Prostatic hyperplasia
Urinary continence ability
Serum testosterone
Postoperative complications
Transurethral plasma kinetic enucleation of prostate
