摘要
目的:通过Meta分析探索导致老年髋部骨折患者术后谵妄的危险因素。方法:在中国生物医学文献数据库、万方、知网、维普、Pubmed、Cochrane图书馆、Embase、Web of science中检索有关老年髋部骨折患者术后谵妄的相关研究,通过进行文献质量评价,应用RevMan 5.3分析软件进行敏感性和异质性分析,并采用固定效应或随机效应模型计算合并后的综合效应。结果:纳入14篇文献,Meta分析显示:年龄、术前认知功能受损、术前合并基础疾病≥3种、糖尿病史、术前白蛋白<35 g/L、术前身体质量指数(Body Mass Index,BMI)<20 kg/m2、术前等待时间≥4 d、全身麻醉、手术时间是老年髋部骨折术后谵妄的危险因素,术前C-反应蛋白(C-reactive Protein,CRP)水平与老年髋部骨折术后谵妄的发生无明显相关性。
Objective: To evaluate the risk factors for postoperative delirium in elderly hip fracture patients. Methods: Relevant studies on postoperative delirium in elderly patients with hip fracture were searched in CBM, Wanfang, CNKI, VIP, PubMed, Cochrane Library, Embase and Web of Science. Through literature quality evaluation, sensitivity and heterogeneity were analyzed by RevMan 5.3,and cumulative effects were calculated by either fixed effect or random effect models. Results: 14 studies were included. The results of meta-analysis showed that: age, preoperative cognitive dysfunction, preoperative complications≥3, history of diabetes mellitus, preoperative albumin<35 g/L, preoperative BMI<20 kg/m2, preoperative preparation time≥4 d, general anesthesia, and operation time were the risk factors of postoperative delirium of elderly hip fracture patients. There was no significant correlation between preoperative CRP level and postoperative delirium of elderly patients with hip fracture.
作者
刘佳丽
赵昱东
朱明双
LIU Jiali;ZHAO Yudong;ZHU Mingshuang
出处
《中医临床研究》
2022年第9期111-115,共5页
Clinical Journal Of Chinese Medicine
关键词
老年髋部骨折
谵妄
危险因素
META分析
Elderly patients with hip fracture
Delirium
Risk factor
Meta-analysis
