摘要
目的探讨乳腺癌超声征象及其术后复发的危险因素。方法回顾性分析2018年1月至2019年6月在苏州市第九人民医院接受根治性手术治疗的女性乳腺癌患者174例(共188个乳腺原发性癌灶)的临床资料。根据患者术后随访是否复发分为复发组和非复发组,比较2组乳腺超声征像,采用Logistic回归分析乳腺癌超声征像在患者术后复发中的影响状况。结果174例患者术后随访中,6例失访(共7个乳腺原发性癌灶),50例复发共54个乳腺原发性癌灶(复发组),占比29.83%(54/181)。复发组与非复发组在肿瘤最大直径、边缘、纵横比、钙化、Alder血流分级方面的比较,差异有统计学意义(P<0.05)。Logistic回归分析显示肿瘤直径≥3 cm(OR=1.514,95%CI:1.257~3.209)、边缘模糊(OR=3.497,95%CI:1.926~5.473)、纵横比>1(OR=1.718,95%CI:1.148~4.376)、钙化(OR=1.872,95%CI:1.162~2.894)、Alder血流Ⅱ~Ⅲ级(OR=1.404,95%CI:1.053~2.617)均是乳腺癌术后复发的危险因素(P<0.05)。结论肿瘤直径≥3 cm、肿瘤边缘模糊、纵横比>1、肿瘤内钙化、Alder血流Ⅱ~Ⅲ级的乳腺癌患者术后复发风险较高。
Objective To explore the ultrasound signs of breast cancer and the risk factors for postoperative recurrence.Methods A total of 188 primary breast cancer foci of 174 female breast cancer patients who received radical surgery in Suzhou Ninth People's Hospital from January 2018 to June 2019 were selected as the research objects.Patients were divided into recurrence group and non-recurrence group according to the postoperative follow-up.Compared the two groups of breast ultrasound signs,logistic regression was used to analyze the influence of breast cancer ultrasound signs in patients with postoperative recurrence.Results During the follow-up of 174 patients,6 cases were lost to follow-up(a total of 7 primary breast cancer foci).A total of 54 primary breast cancer foci in 50 cases of recurrence(recurrence group)accounted for 29.83%(54/181).The comparison between the recurring group and the non-recurring group in terms of tumor maximum diameter,margin,aspect ratio,calcification,and Alder blood flow classification was significantly different(P<0.05).Logistic regression analysis showed that tumor diameter≥3 cm(OR=1.514,95%CI:1.257-3.209),blurred edges(OR=3.497,95%CI:1.926-5.473),aspect ratio>1(OR=1.718,95%CI:1.148-4.376),calcification(OR=1.872,95%CI:1.162-2.894),Alder blood flow gradeⅡ-Ⅲ(OR=1.404,95%CI:1.053-2.617)were the risk of breast cancer recurrence after surgery factors(P<0.05).Conclusion Breast cancer patients with tumor diameter≥3 cm,tumor margins fuzzy,aspect ratio>1,intratumoral calcification,Alder blood flow gradeⅡtoⅢbreast cancer patients have a higher risk of postoperative recurrence.
作者
何小芳
周敏
熊朝月
周海兰
朱峰
HE Xiao-fang;ZHOU Min;XIONG Chao-yue;ZHOU Hai-lan;ZHU Feng(Department of Ultrasound,Suzhou Ninth People's Hospital,Soochow 215200,Jiangsu,China)
出处
《东南国防医药》
2022年第3期274-277,共4页
Military Medical Journal of Southeast China
关键词
乳腺癌
超声
术后复发
危险因素
breast cancer
ultrasound
postoperative recurrence
risk factors
