摘要
目的探讨定志方治疗老年脑卒中后抑郁的效果。方法84例脑卒中后抑郁患者,随机分为对照组(40例)和定志方组(44例)。对照组采用常规抗抑郁药物治疗,定志方组在对照组基础上增加定志方治疗。比较两组治疗前后的汉密顿抑郁量表(HAMD)、汉密顿焦虑量表(HAMA)、躯体化症状问卷(SSI)、简易精神状态检查表(MMES)、综合评定量表(GQOLI-74)评分。结果治疗后,两组HAMD、HAMA评分均低于治疗前,且定志方组HAMD(16.06±1.96)分、HAMA(17.56±2.43)分均低于对照组的(20.34±2.45)、(20.19±3.52)分,差异有统计学意义(P<0.05)。治疗后,两组SSI评分均低于治疗前,MMES、GQOLI-74评分均高于治疗前,且定志方组SSI评分(25.03±2.03)分低于对照组的(34.67±3.14)分,MMES评分(28.36±7.26)分、GQOLI-74评分(87.61±12.03)分高于对照组的(23.56±5.05)、(72.37±10.58)分,差异有统计学意义(P<0.05)。结论常规抗抑郁药物基础上联合定志方治疗老年脑卒中后抑郁,可有效改善患者抑郁与焦虑症状,并可缓解躯体化症状,提升认知功能和生活质量。
Objective To discuss the effect of Dingzhi prescription on senile post-stroke depression.Methods A total of 84 patients with post-stroke depression were randomly divided into control group(40 cases)and Dingzhi prescription group(44 cases).The control group was treated with conventional antidepressants,and the Dingzhi prescription group was additionally treated with Dingzhi prescription on the basis of the control group.Both groups were compared in terms of Hamilton depression scale(HAMD)score,Hamilton anxiety scale(HAMA)score,somatization symptom inventory(SSI),mini-mental status examination(MMES),and generic quality of life inventory-74(GQOLI-74)score.Results After treatment,the HAMD and HAMA scores of the two groups were lower than those of this group before treatment,and the HAMD score(16.06±1.96)points and HAMA score(17.56±2.43)points of the Dingzhi prescription group were lower than(20.34±2.45)and(20.19±3.52)points of the control group.All the differences were statistically significant(P<0.05).After treatment,the SSI score of the two groups were lower than those of this group before treatment,and the MMES score and GQOLI-74 score were higher than those of this group before treatment;the SSI score(28.36±7.26)points and GQOLI-74 score(87.61±12.03)points were higher than(23.56±5.05)and(72.37±10.58)points of the control group;all the differences were statistically significant(P<0.05).Conclusion Dingzhi prescription on the basis of conventional antidepressant treatment in elderly patients with post-stroke depression can effectively improve the symptoms of depression and anxiety,relieve somatization symptoms,and improve cognitive function and quality of life.
作者
郑微
ZHENG Wei(Dandong Hospital of Traditional Chinese Medicine,Dandong 118000,China)
出处
《中国现代药物应用》
2022年第8期162-164,共3页
Chinese Journal of Modern Drug Application
关键词
定志方
脑卒中
抑郁
认知功能
躯体化症状
Dingzhi prescription
Stroke
Depression
Cognitive function
Somatization symptoms
