摘要
指出了小白菊内酯具有抗炎免疫调节、增加癌细胞的敏感性,从而提高细胞抗肿瘤活性等多种药用作用。采用超声提取、溶剂萃取、微波提取3种不同方法提取了惠白菊中的小白菊内酯,利用高效液相色谱含量进行了含量测定。结果表明:微波提取法提取小白菊内酯效率最高,进一步对其提取方法进行正交优化,得出最佳提取条件为:甲醇浓度为70%,料液比为1∶5,微波40s,此时测定的小白菊内酯含量为2.106 mg/g。
Parthenolide has many medicinal effects,such as anti-inflammatory and immune regulation,increasing the sensitivity of cancer cells,so as to improve the antitumor activity of cells.In this paper,three different methods of ultrasonic extraction,solvent extraction and microwave extraction were used to extract the parthenolide from Huibai Chrysanthemum.The content was determined by HPLC.It was found that the microwave extraction method had the highest extraction efficiency.The orthogonal optimization of the extraction method was carried out.The optimum extraction conditions were as follows:methanol concentration of 70%,solid-liquid ratio of 1:5 and microwave for 40s.At this time,the content of parthenolide was 2.106 mg/g.
作者
陈润泽
吴涛
于德江
赵晓雪
杨欣萍
赵美丽
白起林
任丽丽
Chen Runze;Wu Tao;Yu Dejiang;Zhao Xiaoxue;Yang Xinping;Zhao Meili;Bai Qilin;Ren Lili(Shandong Provincial Engineering and Technology Research Center for Wild Plant Resources Development and Application of Yellow River Delta,Binzhou,Shandong 256600,China;Shandong Provincial Key Laboratory of Eco-Environmental Science for Yellow River Delta,Binzhou,Shandong 256600,China;College of Biological and Environmental Engineering,Binzhou University,Binzhou,Shandong 256600,China)
出处
《绿色科技》
2022年第10期264-266,共3页
Journal of Green Science and Technology
基金
山东省大学生创新训练项目(编号:S202110449142)。
关键词
惠白菊
小白菊内酯
微波提取
Huibai Chrysanthemum
parthenolide
microwave extraction
