摘要
目的:探讨肝脏瞬时弹性成像检测预测乙肝肝硬化患者预后的价值。方法:选取2016年1月~2021年1月于深圳市松岗人民医院确诊的乙型肝炎肝硬化患者52例,根据患者预后分为A、B两组,无并发症患者纳入A组,有并发症患者纳入B组。使用瞬间弹性扫描仪对患者肝脏硬度进行检测,并使用Child-Pugh对患者肝脏储备功能进行分级评价。比较不同组患者的肝脏硬度检查结果。结果:A组患者的肝脏硬度和脂肪衰减水平均低于B组患者(P<0.05)。不同Child-Pugh分级患者肝脏硬度和脂肪衰减水平差异具有统计学意义(P<0.05)。进一步两两比较显示,Child-Pugh A级患者肝脏硬度和脂肪衰减水平最低,Child-Pugh C级患者肝脏硬度和脂肪衰减水平最高(P<0.05)。结论:瞬时弹性成像能够有效检测肝脏硬度,该指标水平与Child-Pugh肝功能分级、是否发生并发症有关,具有一定的临床意义,可作为早期预测乙型肝炎肝硬化患者预后的辅助检查手段。
Objective:To explore the value of liver transient elastography in predicting the prognosis of patients with hepatitis B cirrhosis.Methods:52 patients with hepatitis B cirrhosis diagnosed in Shenzhen Songgang People’s Hospital from January 2016 to January 2021 were selected and divided into group A and group B according to the prognosis of patients.Patients without complications were included in group A,and patients with complications were included in group B.The liver stiffness was measured by instantaneous elastic scanner,and the liver reserve function was graded by Child-Pugh.The liver hardness test results of different groups were compared.Results:The liver hardness and fat attenuation levels of group A were lower than those of group B(P<0.05).There were significant differences in liver stiffness and fat attenuation levels among different Child-Pugh grades(P<0.05).Further pairwise comparison showed that the liver hardness and fat attenuation levels of Child-Pugh A patients were the lowest,while those of Child-Pugh C patients were the highest(P<0.05).Conclusions:Transient elastography can effectively detect liver stiffness,which is related to Child-Pugh liver function classification and complications.It has a certain clinical significance,and can be used as an auxiliary means to early predict the prognosis of patients with hepatitis B cirrhosis.
作者
杨祯玲
雷平光
YANG Zhen-ling;LEI Ping-guang(Department of Gastroenterology,Songgang People’s Hospital,Baoʼan District,Shenzhen,Guangdong Shenzhen 518100)
出处
《中国医疗器械信息》
2022年第10期11-13,共3页
China Medical Device Information
关键词
乙型肝炎
病毒
肝硬化
预后
hepatitis B
viruses
cirrhosis
prognosis
