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探讨腹腔镜侧脑室-腹腔分流术治疗梗阻性脑积水的疗效及对预后康复效率、炎症因子的影响 被引量:2

The Efficacy of Laparoscopic Lateral Ventriculoperitoneal Shunt in the Treatment of Obstructive Hydrocephalus and Its Effect on Prognosis,Rehabilitation Efficiency and Inflammatory Factors
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摘要 目的:探讨腹腔镜侧脑室-腹腔分流术(LVPS)治疗梗阻性脑积水的临床价值。方法:选取2018年1月-2021年12月某院70例梗阻性脑积水患者,随机分为研究组(采用LVPS治疗)和对照组(采用VPS治疗)各35例,比较两组手术前后的降钙素原(PCT)、日常生活能力评定量表(ADL)、血清淀粉样蛋白(SAA)、匹兹堡睡眠质量指数(PSQI)、超敏C-反应蛋白(hs-CRP),术后2个月的康复效果及并发症。结果:术前两组的PCT、ADL、hs-CRP、PSQI、SAA差异无统计学意义(P>0.05),术后1周研究组的PCT、hs-CRP、PSQI、SAA水平低于对照组,ADL高于对照组,术后2个月研究组的康复优良率(94.29%vs 77.14%)高于对照组,差异有统计学意义(P<0.05);两组的术后并发症发生率(8.57%vs 22.86%)差异无统计学意义(P>0.05)。结论:LVPS可提高梗阻性脑积水患者术后身体康复效率,降低患者感染风险,改善患者生活质量。 Objective:To investigate the clinical value of laparoscopic lateral ventriculoperitoneal shunt(LVPS)in the treatment of obstructive hydrocephalus.Methods:70 patients with obstructive hydrocephalus in a hospital from January 2018 to December 2021 were selected and randomly divided into study group(35 cases,treated with LVPS)and control group(35 cases,treated with VPS).The levels of procalcitonin(PCT),activity of daily living scale(ADL),serum amyloid(SAA),Pittsburgh sleep quality index(PSQI)and high-sensitivity C-reactive protein(hs-CRP)before and after operation were compared between the two groups.The rehabilitation effect and complications two months after operation were also compared between the two groups.Results:There was no significant difference in PCT,ADL,hs-CRP,PSQI and SAA between the two groups before operation(P>0.05).The levels of PCT,hs-CRP,PSQI and SAA in the study group were lower than those in the control group one week after operation,and ADL was higher than that in the control group.The excellent and good rate of rehabilitation in the study group was higher than that in the control group two months after operation(94.29%vs 77.14%),and the difference was statistically significant(P<0.05).There was no statistically significant difference in the incidence of postoperative complications between the two groups(8.57%vs 22.86%)(P>0.05).Conclusion:LVPS can improve the postoperative physical rehabilitation efficiency,reduce the risk of infection and improve the quality of life of patients with obstructive hydrocephalus.
作者 余志豪 Yu Zhihao(Guangshan People's Hospital,Xinyang 465450)
机构地区 光山县人民医院
出处 《数理医药学杂志》 CAS 2022年第6期802-805,共4页 Journal of Mathematical Medicine
关键词 梗阻性脑积水 腹腔镜侧脑室-腹腔分流术 炎症因子 obstructive hydrocephalus laparoscopic lateral ventriculoperitoneal shunt inflammatory factors
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