摘要
食品安全与人民健康息息相关,食品安全检测技术则是保障食品安全的重要支撑.由于食品基质的复杂性以及痕量有害物质的存在,现有检测技术在灵敏度、特异性、准确性等方面仍面临着严峻的挑战.近年来,单分子检测技术得到了迅速发展,被广泛应用于基因测序、生物传感、疾病检测等领域.其中,纳米孔单分子检测技术具有巨大的潜在应用价值,具有免标记、便携、条件温和等优点,在食品安全检测领域得到了广泛应用,如重金属离子、生物毒素、抗生素、农药残留、非法添加剂等危害物的检测.本文重点介绍了纳米孔技术的传感原理、纳米孔的类别以及在食品安全检测领域的应用进展,并对今后纳米孔技术在食品安全检测领域的发展前景进行了展望.
Food safety is closely related to public health,and food safety monitoring technology is a solid foundation for ensuring food safety.Due to the complexity of the food matrix and the presence of trace amounts of harmful substances,existing detection technologies still have challenges in terms of sensitivity,specificity,and accuracy.In recent years,single molecule detection technology has developed rapidly and is widely used in fields such as gene sequencing,biosensing,and disease diagnosis.Among them,nanopore sensing is a relatively simple single-molecule technology that has the advantages of label-free,portable,and nondestructive.It has been applied in the detection of hazardous substances in food,such as heavy metal ions,biotoxins,antibiotics,pesticide residues,as well as illegal additives.In this article,we introduce the sensing principles of nanopore technology,the classification of nanopores,and the application progress in food safety monitoring.Finally,we summarize the current research status and discuss the future development of nanopore technology in food safety applications.
作者
苏卓群
李童
李国梁
SU Zhuoqun;LI Tong;LI guoliang(School of Food and Biological Engineering,Shaanxi University of Science and Technology,Xi'an 710021,China)
出处
《未来食品科学》
2021年第4期44-55,共12页
Future Food Science
基金
国家自然科学基金优秀青年科学基金项目(32022069)。
关键词
食品安全
纳米孔
单分子技术
食品污染物检测
food safety
nanopore
single molecule technology
food contaminants detection
