摘要
胆胰汇合异常(pancreaticobiliary maljunction,PBM)是胰管和胆管在胚胎时期开始在十二指肠壁外连接,由此形成胆汁和胰液异常返流并产生相应的临床症状的一类先天性疾病.PBM是胆道恶性肿瘤的高危因素.PBM可伴有或不伴有胆管扩张症(biliary dilatation,BD).早期诊断PBM有助于预防相关并发症;超声、磁共振、螺旋CT、内镜超声、内窥镜逆行胰胆管造影(endoscopic retrograde cholangiopancreatography,ERCP)、胆道造影等是重要的诊断手段.胆管囊肿完全切除和胆肠重建术是治疗PBM合并BD的标准术式;不合并胆管扩张症的PBM应及时行胆囊切除术.
Pancreaticobiliary maljunction(PBM)is a congenital anomaly that is defined as a junction of the pancreatic and bile ducts located outside the duodenal wall during the embryonic stage,resulting in bile and pancreatic juice reflux and corresponding clinical symptoms.PBM is a high risk factor for cholangiocarcinoma.PBM can occur with or without biliary dilatation(BD).Early diagnosis of PBM can prevent complications.Ultrasonography,magnetic resonance imaging,multi-slice spiral computed tomography,endoscopic ultrasonography,endoscopic retrograde cholangiopancreatography,and cholangiopancreatography are important modalities for diagnosis of this disease.The standard surgical procedure for PBM with BD is dilated cholangiectomy and choledochoenteroreconstruction.Cholecystectomy should be performed as early as possible for PBM without BD.
作者
蔡强
喻诗哲
喻智勇
Qiang Cai;Shi-Zhe Yu;Zhi-Yong Yu(Department of Hepatobiliary Surgery,Affiliated Hospital of Yunnan University,Kunming 650021,Yunnan Province,China;Department of Hepatobiliary Surgery,The First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,Henan Province,China)
出处
《世界华人消化杂志》
CAS
2022年第11期498-503,共6页
World Chinese Journal of Digestology
基金
云南省王曙光专家工作站,No.2018IC107.
关键词
胆胰汇合异常
胆管扩张症
胚胎学
诊断
治疗
Pancreaticobiliary maljunction
Biliary dilatation
Embryology
Diagnosis
Therapy
