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一起幼儿园札如病毒感染暴发调查

Investigation on an outbreak of Sapovirus infection in kindergarten
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摘要 目的明确一起幼儿园胃肠炎暴发疫情的病原体,找到传染来源和传播因素.方法采用现场流行病学调查步骤即拟定病例定义,开展搜索病例并作描述性研究,结合现场调查情况形成假设,采用病例对照研究分析危险因素;采集病例的呕吐物、肛拭子、粪便作病原学检测.结果从2017年12月1日-12月15日共发生病例18例,主要症状是呕吐、腹痛等(均占83.33%),均为中四班幼儿,班级罹患率为48.65%(18/37).采集患儿8份粪便,经PCR检测,5份粪便札如病毒阳性.病例对照研究显示与患病幼儿有肢体接触为发病危险因素[OR=6.88,95%CI(1.48-32.01)].经及时采取有效防控措施,疫情得到及时控制.结论这是一起札如病毒感染性胃肠炎暴发疫情,传播的主要原因是未及时发现并隔离首例病例及幼儿之间密切的肢体接触. Objective To identify the pathogen of an outbreak of gastroenteritis in kindergarten and find out the source of infection and transmission factors.Met hods Field epidemiological investigation steps were adopted,that is,to develop the case definition,to carry out case search and descriptive research,to form hypothesis combined with field investigation,and to analyze the risk factors by casecontrol study;vomit,anal swab and feces were collected for etiological detection.Results From December 1 to December 15,2017,a total of 18 cases occurred the main symptoms were vomiting and abdominal pain(83.33%).All of them were children in Middle Four class the incidence rate in class was 48.65%(18/37).8 feces were collected from the children,and 5 feces were positive for Sapovirus by PCR the case-control study showed that physical contact with sick children was a risk factor,and its OR value(95%CI)was 6.88[95%CI(1.48-32.01)].After taking effective prevention and control measures in time,the epidemic situation was controlled in time.C on elusion This is an outbreak of Sapovirus gastroenteritis.The main reasons for its spread are not finding and isolating the first case in time and the close physical contact between children.
作者 李基 王永 李晓峰 张敏 李苑 Li Ji;Wang Yong;Li Xiaofeng;Zhang Min;Li Yuan(Shenzhen Bao'an Distriet Public Health Service Center,Guangdong Shenzhen 518108;Shenzhen Bao'an Distriet Center for Disease ControI and Prevent ion,Guangdong Shenzhen 518101)
出处 《首都食品与医药》 2022年第10期75-77,共3页 Capital Food Medicine
关键词 札如病毒 急性胃肠炎 幼儿 暴发 Sapovirus Acute gastroenteritis Young Children Outbreak
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