摘要
目的:比较超声检查与SPECT/CT显像在分化型甲状腺癌(DTC)术后残留甲状腺组织诊断中的应用价值。方法:选择完成手术治疗的DTC患者82例为研究对象。记录所有患者^(131)I剂量与血清促甲状腺激素(TSH)、甲状腺球蛋白(Tg)水平。术后6个月进行超声检查与SPECT/CT显像,判断术后残留甲状腺组织情况。结果:在82例患者中,术后发生残留甲状腺组织12例(残留组),发生率为14.6%,未发生残留甲状腺组织70例(非残留组)。残留组^(131)I剂量及血清TSH、Tg水平高于非残留组(均P<0.05)。SPECT/CT显像诊断术后残留甲状腺组织的准确率高于超声检查(P<0.05)。ROC曲线分析显示,超声与SPECT/CT显像诊断DTC术后残留甲状腺组织的曲线下面积分别为0.635和0.899,约登指数分别为0.625和0.833。结论:相对于超声检查,SPECT/CT显像对DTC术后残留甲状腺组织的诊断价值更高,能及时发现残留部位。
Objective:To compare the value of ultrasonography and SPECT/CT imaging in the diagnosis of residual thyroid tissue after differentiated thyroid carcinoma(DTC)surgery.Methods:A total of 82 patients with DTC who completed the surgical treatment were selected as the study subjects.The dose of ^(131)I and the levels of serum thyroid stimulating hormone(TSH)and thyroglobulin(Tg)were recorded in patients.Ultrasonography and SPECT/CT imaging were performed 6 months after operation to determine the residual thyroid tissue.Results:Of the 82 patients,12 had residual thyroid tissue(residual group),with an incidence rate of 14.6%,and 70 had no residual thyroid tissue(non-residual group).The ^(131)I dose,serum TSH and Tg levels in the residual group were higher than those in the non-residual group(all P<0.05).The accuracy of SPECT/CT imaging in the diagnosis of postoperative residual thyroid tissue was higher than that of ultrasonography(P<0.05).ROC curve analysis showed that the area under the curve of residual thyroid tissue after DTC diagnosis by ultrasonography and SPECT/CT imaging was 0.635 and 0.899 respectively,and the Youden index was 0.625 and 0.833 respectively.Conclusion:Compared with ultrasonography,SPECT/CT imaging has higher diagnostic value for residual thyroid tissue after DTC surgery,and can find the residual site in time.
作者
戚新春
朱洁
QI Xinchun;ZHU Jie(Department of Head and Neck Oncology,Shaanxi Provincial Cancer Hospital,Xi'an 710061,China)
出处
《陕西医学杂志》
CAS
2022年第6期709-712,共4页
Shaanxi Medical Journal
基金
陕西省重点研发计划项目(2021SF-011)。
