摘要
目的分析磁共振成像联合磁共振波普分析技术在脑胶质瘤复发、假性进展和放射性脑损伤中鉴别诊断的运用价值。方法采用回顾性分析法。回顾2017年1月至2021年1月期间进行脑胶质瘤术后放射性治疗患者57例,在放射性治疗后经影像学检查存在异常强化病灶,并分别进行磁共振成像(MRI)、磁共振波普分析技术(MRS)检查,观察病灶强化区具体影像学表现,根据病理及随访结果,分析两种影像学技术的鉴别价值。结果MRI联合MRS对脑胶质瘤放射性治疗后复发、假性进展以及放射性脑损伤检出灵敏度、特异度及准确性分别为88.0%、91.67%、91.23%,均高于单独MRI技术的45.45%、62.50%、52.63%,差异有统计学意义(P<0.05)。脑胶质瘤复发患者Cho/Cr、Cho/NAA高于假性进展、放射性脑损伤组,NAA/Cr低于假性进展、放射性脑损伤组差异有统计学意义(P<0.05),但假性进展组与放射性脑损伤组的Cho/Cr、Cho/NAA、NAA/Cr比较,差异无统计学意义(P>0.05)。结论磁共振成像联合磁共振波普分析技术对脑胶质瘤复发、假性进展和放射性脑损伤患者有较高的鉴别诊断价值,对临床诊治有重要意义。
Objective To analyze the application value of magnetic resonance imaging combined with magnetic resonance spectroscopy in the differential diagnosis of recurrence,pseudo-progression and radiation brain injury of glioma.Methods Retrospective analysis was used.A review of 57 patients who underwent postoperative radiotherapy for glioma from January 2017 to January 2021.After radiotherapy,there were abnormally enhanced lesions on imaging examination,and magnetic resonance imaging(MRI)and magnetic resonance were performed respectively.Pop analysis technology(MRS)examination,observe the specific imaging manifestations of the focus of the enhancement area,and analyze the differential value of the two imaging techniques based on the pathological and follow-up results.Results The sensitivity,specificity and accuracy of MRI combined with MRS in the detection of glioma recurrence,pseudoprogression and radiation-induced brain injury after radiotherapy were as follows:88.0%,91.67%,91.23%,which all were higher than 45.45%,62.50%,52.63%of MRI alone,the difference was statistically significant(P<0.05).The Cho/Cr and Cho/NAA of patients with recurrence of glioma were higher than those in the pseudo-progressive and radiationinduced brain injury group,NAA/Cr was lower than the pseudo-progressive,and the difference in the radiation-induced brain injury group was statistically significant(P<0.05),but the difference was statistically significant(P<0.05).There was no significant difference in Cho/Cr,Cho/NAA,NAA/Cr between the sexual progression group and the radiation brain injury group(P>0.05).Conclusion Magnetic resonance imaging combined with magnetic resonance spectroscopy has a high differential diagnosis value for patients with glioma recurrence,pseudo-progression and radiation-induced brain injury,and is of great significance for clinical diagnosis and treatment.
作者
孙飞月
李云
SUN Fei-yue;LI Yun(Nuclear Magnetic Room,Seventh People's Hospital of Zhengzhou,Zhengzhou 450000,Henan Province,China)
出处
《罕少疾病杂志》
2022年第6期22-25,共4页
Journal of Rare and Uncommon Diseases
关键词
磁共振成像
磁共振波普分析技术
脑胶质瘤
复发
假性进展
放射性脑损伤
Magnetic Resonance Imaging
Magnetic Resonance Pop Analysis Technique
Glioma
Recurrence
False Progression
Radiation Brain Injury
