摘要
目的:探究胆结石并发胆囊炎患者行腹腔镜治疗后的临床效果以及对肿瘤坏死因子-α(TNF-α)等指标的影响。方法:将陇南市第一人民医院收治的胆结石并发胆囊炎患者作为此次研究的主要对象,随机分为两组,每组55例。对照组采传统开腹手术治疗,观察组采取腹腔镜治疗,并将两组治疗后的各项指标进行对比,以明确治疗效果。结果:观察组出血量少于对照组、切口长度和手术时间均短于对照组,差异均有统计学意义(P<0.05)。观察组疼痛评分低于对照组,术后排气时间、下床活动时间、住院时间均短于对照组,差异均有统计学意义(P<0.05)。两组经治疗后,TNF-α水平均明显升高,白介素-6、白介素-10水平均明显降低,但观察组升高和降低趋势均优于对照组,差异均有统计学意义(P<0.05)。结论:腹腔镜治疗胆结石并发胆囊炎患者效果显著,且能够有效改善机体炎症因子状态,值得研究和推广。
Objective: To explore the clinical effect analysis of laparoscopic treatment in patients with cholelithiasis complicated with cholecystitis and its influence on tumor necrosis factor-α (TNF-α) and other indicators. Methods: Patients with cholelithiasis complicated with cholecystitis admitted to Longnan First People's Hospital were selected as the main subjects of this study. They were randomly divided into two groups with 55 cases in each group. The control group was treated with traditional laparotomy, and the observation group was treated with laparoscopic treatment. Various indicators after treatment in the two groups were compared to clarify the treatment effect. Results: The blood loss of the observation group was lower than that of the control group, the incision length and operation time of the observation group were shorter than those of the control group, with statistically significant differences (PP<0.05). The pain score of the observation group was lower than that of the control group, and the postoperative exhaust time, ambulation time, and hospital stay were shorter than those of the control group, with statistically significant differences (P<0.05). After treatment, the levels of TNF α in the two groups were significantly increased, and the levels of interleukin-6 and interleukin-10 were significantly decreased, but the increase and decrease trends in the observation group were better than those in the control group, with statistically significant differences (P<0.05). Conclusion: Laparoscopic treatment of patients with cholelithiasis complicated with cholecystitis has a significant effect, and can effectively improve the state of inflammatory factors in the body, which is worthy of research and promotion.
作者
杨爱福
Yang Ai-fu(Longnan First People's Hospital,Longnan 746000,Gansu Province,China)
出处
《中国社区医师》
2022年第11期30-32,共3页
Chinese Community Doctors
关键词
胆结石并发胆囊炎
腹腔镜治疗
肿瘤坏死因子-Α
Cholelithiasis complicated with cholecystitis
Laparoscopic treatment
Tumor necrosis factor-α
