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奥沙利铂联合胸腺肽治疗肺癌恶性胸腔积液的临床疗效

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摘要 目的:探讨奥沙利铂联合胸腺肽治疗肺癌恶性胸腔积液的疗效。方法:将我院肿瘤科收治的40例肺癌恶性胸腔积液患者按数表法随机分为两组,对照组给予胸腔内灌注奥沙利铂,观察组使用胸腔内灌注奥沙利铂联合胸腺肽,对比两组的近期疗效、T淋巴细胞水平变化、不良反应。结果:观察组临床获益率为90.00%,明显高于对照组的70.00%(P<0.05);观察组治疗后CD3^(+)、CD4^(+)、CD8^(+)水平均高于对照组(P<0.05);两组骨髓抑制、胸痛、消化道不适、肝肾损害等不良反应发生率无明显差异(P>0.05)。结论:肺癌恶性胸腔积液给予奥沙利铂联合胸腺肽治疗后效果明显提升,且不良反应可控,具有积极的临床意义。
作者 涂微
出处 《北方药学》 2021年第10期153-153,174,共2页 Journal of North Pharmacy
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