摘要
目的评估卵圆孔未闭(PFO)介入封堵术的临床疗效、安全性及对偏头痛患者的影响。方法选择2020年5-11月在该院行介入封堵术的65例PFO患者,包括偏头痛36例,脑梗死11例,房间隔膨胀瘤(ASA)5例,不明原因晕厥10例,根据卵圆窝的大小及是否合并ASA等选用不同大小的PFO封堵器行介入治疗。偏头痛患者术前、术后及术后1个月行头痛影响测定-6(HIT-6)评分。结果64例PFO患者成功进行了介入封堵治疗,成功率98.5%,1例患者导丝未能成功通过卵圆孔放弃封堵。术中及术后无严重并发症发生。36例偏头痛患者封堵术后偏头痛症状均有不同程度缓解,未出现新发脑梗死。结论介入封堵治疗PFO安全有效,封堵术后偏头痛患者头痛症状明显缓解或消失,远期效果尚需进一步随访研究。
Objective To evaluate the clinical efficacy and safety of interventional occlusion of patent foramen ovale(PFO)and effect in migraine patients.Methods Sixty-five patients with PFO undergoing interventional occlusion in this hospital from May 2020 to November 2020 were selected,including 36 cases of migraine,11 cases of cerebral infarction,5 cases of atrial septal aneurysm(ASA),and 10 cases of unexplained syncope.The interventional therapy was performed with different sizes of occluders according to the size of fossa ovalis and whether complicating ASA.The patients with migraine received the headache impact test(HIT)-6 scoring before and after operation and in postoperative 1 month.Results All 64 cases of PFO were successfully treated with interventional occlusion.The success rate was about 98.5%.One case gave up interventional occlusion due to the guidewire failed to pass the foramen ovalis.No serious complications occurred during and after the operation.All the 36 migraine patients had different degrees of migraine relief after occlusion,and no new cerebral stroke was found.Conclusion Interventional occlusion of PFO is safe and effective,and the headache symptoms of migraine patients after closure can be significantly relieved or disappeared,but the long-term effect still needs further follow-up study.
作者
张长海
刘晓桥
张萍
谭洪文
梁勤
卜婕
刘兴会
杜发旺
王纪人
刘会
李天纵
王咏梅
赵昌莉
ZHANG Changhai;LIU Xiaoqiao;ZHANG Ping;TAN Hongwen;LIANG Qin;BU Jie;LIU Xinghui;DU Fawang;WANG Jiren;LIU Hui;LI Tianzong;WANG Yongmei;ZHAO Changli(Department of Cardiovascular Medicine,Guizhou Provincial People′s Hospital,Guiyang,Guizhou 550002,China)
出处
《重庆医学》
CAS
2022年第10期1726-1730,共5页
Chongqing medicine
基金
贵州省科技厅-贵州省人民医院联合基金资助项目[黔科合LH字(2016)7180号]。
关键词
卵圆孔未闭
右心声学造影
右向左分流
介入封堵术
偏头痛
patent foramen ovale
right heart angiography
right to left shunt
interventional occlusion
migraine
