摘要
肥胖是由遗传因素、环境因素等多种因素相互作用所致,肥胖者往往存在肠道菌群紊乱的现象,但目前关于肠道菌群影响肥胖的具体机制尚无定论,可能涉及脂肪组织褐化、能量积累、炎症反应、短链脂肪酸、肠道屏障等。本文就肠道菌群影响肥胖的机制进行综述,以期进一步阐明二者的联系,为临床治疗肥胖提供参考。
Obesity is caused by the interaction of genetic factors,environmental factors and other factors.Obesity often has the phenomenon of intestinal flora disorder.However,the specific mechanism of intestinal flora affecting obesity is still unclear,which may involve adipose tissue browning,energy accumulation,inflammatory response,short chain fatty acids,intestinal barrier and so on.This article reviews the mechanism of intestinal flora affecting obesity,in order to further clarify the relationship between the two,and provide reference for clinical treatment of obesity.
作者
向姣姣
李国娟
杨通艳
黄雨婷
XIANG Jiao-jiao;LI Guo-juan;YANG Tong-yan;HUANG Yu-ting(Department of Endocrinology,the Affiliated Nanhua Hospital,Hengyang Medical School,University of South China,Hengyang 421000,Hunan,China)
出处
《医学信息》
2022年第10期70-73,共4页
Journal of Medical Information
关键词
肥胖
肠道菌群
脂肪组织
Obesity
Intestinal flora
Adipose tissue