摘要
目的探讨急性白血病合并糖尿病的临床疗效。方法累计在2017年8月至2019年8月抽取急性白血病患者80例,依据选取患者是否合并糖尿病的情况进行分组,合并糖尿病的40例患者被划分为观察组,余下40例单纯急性白血病患者划分为对照组,所选取患者均接受化疗、降血糖治疗、辅助治疗等,对比整个治疗过程中两组患者的并发症发生情况、糖尿病症状、临床转归、生存时间及病死率等指标。结果①数据显示,整个治疗过程中观察组内患者出现各类并发症的概率明显高于对照组,差异有统计学意义(P<0.05)。②对照组无一例出现多饮、多食、多尿现象,观察组内出现上述现象的患者有2例,占总选取患者的5.00%。差异无显著性(P>0.05)。③临床转归统计数据显示,观察组内完全缓解的患者相较于对照组无显著差异(P>0.05),两组患者的生存时间及病死率对比,观察组明显优于对照组,差异有统计学意义(P<0.05)。结论急性白血病合并糖尿病患者相较于单纯急性白血病患者,具有糖尿病症状不明显、感染率高、病死率高的特点,临床治疗难度较大,需要加以重视,及时发现急性白血病合并糖尿病患者并开展感染预防、营养支持等辅助治疗,预防并发症的出现,提高患者的生存质量。
Objective To study the clinical effect of acute leukemia with diabetes mellitus.Methods A total of 80 patients with acute leukemia were selected from August 2017 to August 2019.According to the conditions of patients with diabetes,40 patients with diabetes were divided into the observation group and the remaining 40 patients with simple acute leukemia were divided into the control group.All the selected patients received chemotherapy,hypoglycemic therapy and adjuvant treatment,etc.,which compared the occurrence of complications,diabetes symptoms,clinical conversion,survival time and mortality between the two groups during the whole treatment process.Results(1)Comparative data showed that the probability of various complications in the observed group was significantly higher than in the control group,and the difference between the data was statistically significant(P<0.05).(2)There was no case of polydipsia,polyphagia and polyuria in the control group,and there were 2 cases of the above phenomenon in the observation group,accounting for 5.00%,and the difference was not significant(P>0.05).(3)Statistics of clinical conversion it was shown that there was no significant difference in complete remission within the observed group compared with the control group(P>0.05),with significant advantages over survival time and mortality between the two groups and statistically significant interdata differences(P<0.05).Conclusion Compared with the patients with simple acute leukemia,the patients with acute leukemia and diabetes have the characteristics of not obvious symptoms of diabetes,high infection rate and high mortality.The clinical treatment is difficult,so we need to pay attention to it.We need to find the patients with acute leukemia and diabetes in time and carry out the auxiliary treatment of infection prevention and nutrition support,so as to prevent the occurrence of complications and improve the survival quality of patients Quantity.
作者
蔡威
张丽翡
孙秋岩
CAI Wei;ZHANG Lifei;SUN Qiuyan(Liaoning Health Industry Group Fuxin Mining General Hospital,Fuxin 123000,China)
出处
《中国医药指南》
2022年第13期100-103,共4页
Guide of China Medicine
关键词
急性白血病
糖尿病
化疗
降血糖治疗
Acute leukemia
Diabetes
Chemotherapy
Deglycemic therapy
