摘要
目的探讨脑电生物反馈治疗对老年慢性阻塞性肺疾病(COPD)患者焦虑抑郁及睡眠质量的影响。方法100例老年COPD稳定期患者均分为观察组和对照组,观察组采用常规药物联合生物反馈训练进行治疗,对照组采用常规药物干预治疗,共治疗4周;于治疗前、治疗第2周及第4周时,分别采用抑郁症状自评量表(SDS)评估患者抑郁情况、采用焦虑症状自评量表(SAS)评估患者焦虑程度、匹兹堡睡眠指数(PSQI)评分评价患者睡眠质量,于治疗前及治疗结束时检测患者肺功能、6 min步行距离(6MWT)、体质量指数(BMI)、COPD评估测试(CAT)、改良英国医学研究委员会呼吸困难指数(mMRC)评分及血清白细胞介素-6(IL-6)、C-反应蛋白(CRP)水平。结果治疗前,2组患者SAS、SDS、CAT、PSQI、mMRC评分比较差异无统计学意义(P>0.05);2组患者SAS、SDS及PSQI评分比较,治疗2周时观察组低于对照组、治疗4周时低于治疗2周时,差异有统计学意义(P<0.05);治疗前后,2组患者的肺功能、6MWT、BMI、mMRC评分及血清IL-6、CRP水平比较差异无统计学意义(P>0.05),而CAT评分低于治疗前(P<0.05)。结论脑电生物反馈治疗可明显改善老年COPD合并焦虑抑郁患者情绪状态、睡眠情况、生活质量及健康状况,且治疗时间越长、效果越佳,但对患者的肺功能等指标无明显改善作用。
Objective To investigate the efficacy of electroencephalography bio-feedback treatment for anxiety,depression and sleep quality on elder patients with chronic obstructive pulmonary disease(COPD).Methods One hundred elderly patients with stable COPD were chosen and randomly divided into observation group and control group.Observation group was treated with conventional drugs combined with biofeedback treatment for four weeks;the control group,conventional drug intervention only for four weeks.Before treatment,2 weeks and 4 weeks after intervention,both groups were evaluated with self-rating depression scale(SDS)concerning their degree of depression,their anxiety level by self-rating anxiety scale(SAS),the sleep quality by Pittsburgh sleep quality index(PSQI).Before and after treatment,both groups were checked for pulmonary function,6-min walking distance(6MWT),body mass index(BMI),Improved British Medicine Research Council dyspnea(mMRC)score,leukocyte interleukin-6(IL-6),C-reactive protein(CRP)levels.Results SAS,SDS,CAT,mMRC,and PSQI scores of both groups showed no significant differences before treatment(P>0.05).SAS,SDS and PSQI scores were lower in the observation group than the control group after 2 weeks treatment,differences were statistically significant(P<0.05).There was no significant difference in the pulmonary function,6MWT,BMI,mMRC scores,as well as IL-6 and CRP comparison showed no statistical significance(P>0.05);while CAT score was lower than before treatment(P<0.05).Conclusion The biofeedback treatment can obviously improve the condition of anxiety and depression as well as sleep quality of elderly patients with COPD,so do the sleep quality and health condition.In addition,the longer the treatment time,the better effect.However,there is no significant improvement concerning pulmonary function and other indicators.
作者
马文
邹涛
杨卉
张艳
杨春琼
冯芳
熊莉
MA Wen;ZOU Tao;YANG Hui;ZHANG Yan;YANG Chunqiong;FENG Fang;XIONG Li(Department of Cadre Diagnosis and Treatment&Department of Geriatrics,the Affiliated Hospital of Guizhou Medical University,Guiyang 550004,Guizhou,China;Department of Psychiatric Medicine,the Affiliated Hospital of Guizhou Medical University,Guiyang 550004,Guizhou,China)
出处
《贵州医科大学学报》
CAS
2022年第5期576-580,共5页
Journal of Guizhou Medical University
基金
贵州省科技厅基金(黔科合LH字〔2015〕7429)。
