摘要
玫瑰痤疮发病机制尚未完全阐明,目前认为遗传因素、皮肤局部免疫失衡、神经免疫功能和神经血管环路紊乱、皮肤屏障功能异常、微生物菌群失调等均参与了玫瑰痤疮的发生发展。本文综述玫瑰痤疮的病理生理发病机制研究进展。
The pathogenesis of rosacea has not been fully elucidated.It is currently believed that genetic factors,local skin immune imbalance,neuroimmune and neurovascular dysfunction,skin barrier function abnormalities,microbiota imbalance,etc.,are all involved in the occurrence and development of rosacea.This review summarizes research progress in the pathophysiological pathogenesis of rosacea.
作者
宋晓婷
刘擘
陈玉迪
赵作涛
Song Xiaoting;Liu Bo;Chen Yudi;Zhao Zuotao(Department of Dermatology and Venereology,Peking University First Hospital,National Clinical Research Center for Skin and Immune Diseases,Beijing Key Laboratory of Molecular Diagnosis on Dermatoses,Beijing 100034,China)
出处
《中华皮肤科杂志》
CAS
CSCD
北大核心
2022年第5期446-449,共4页
Chinese Journal of Dermatology
基金
国家自然科学基金中德合作项目(GZ901)。
关键词
红斑痤疮
病理过程
神经免疫调节
局部免疫失衡
神经免疫
皮肤屏障功能
Rosacea
Pathologic processes
Neuroimmunomodulation
Local immunological imbalance
Neuroimmunity
Skin barrier function
