摘要
目的探讨霍奇金淋巴瘤(Hodgkin lymphoma,HL)的临床表现、诊疗要点、误诊原因及防范措施,以提高诊断准确率。方法回顾分析1例诱导淋巴结结核诊断的淋巴瘤患者的临床资料,并复习相关文献。结果本例患者因右锁骨上肿块1年,破溃流脓4个月入院。入院前后多次行穿刺及病理活检等检查,临床诊断为淋巴结结核,予抗结核治疗后症状无明显改善。其后又多次行病理检查,最后一次病理活检确诊为经典霍奇金淋巴瘤,化疗后创面愈合。结论霍奇金淋巴瘤的临床表现缺乏特异性,发生皮肤破溃的情况临床罕见,易与其它特殊感染性创面相混淆,临床诊断时可不断取材进行病理学检查以明确诊断。
Objective To discuss the clinical manifestations,diagnosis and treatment points,causes of misdiagnosis and preventive measures of Hodgkin lymphoma,in order to improve the rate of diagnostic accuracy.Methods To retrospectively analyze the clinical data of a patient with lymphoma diagnosed by induced lymph node tuberculosis,and review the relevant literature.Results The patient was admitted to the hospital with a right supraclavicular mass for 1 year and ulceration for 4 months.Before and after admission,the patient underwent multiple punctures,pathological biopsies and other examinations,the clinical diagnosis was lymph node tuberculosis,and the symptoms did not improve significantly after anti-tuberculosis treatment.Later pathological examinations were performed many times,and the last pathological biopsy confirmed the diagnosis of classic Hodgkin lymphoma,and the wound healed after chemotherapy.Conclusion The clinical manifestations of Hodgkin lymphoma lacks specificity,and the occurrence of skin ulceration is clinically rare,which can be easily confused with other special infectious wounds.In clinical diagnosis,it is possible to continuously obtain materials for pathological examination to clear the diagnosis.
作者
曹丽敏
黄子慧
陈晓钰
高璐珏
洪练青
CAO Limin;HUANG Zihui;CHEN Xiaoyu(Nanjing University of Chinese Medicine Affiliated Nanjing Integrated Traditional Chinese And Western Medicine Hospital,Nanjing,210014)
出处
《实用癌症杂志》
2022年第5期804-806,共3页
The Practical Journal of Cancer
基金
南京市卫计委重点科技项目(编号:ZKX18048)
南京市卫健委青年人才项目(编号:QRX17030)
许芝银全国名中医专家工作室[No,宁口财务2019]26号。
关键词
霍奇金淋巴瘤
误诊
皮肤破溃
鉴别诊断
Hodgkin lymphoma
Misdiagnose
Skin ulceration
Differential diagnosis
