摘要
黑斑息肉综合征(Peutz-Jeghers syndrome,PJS)在幼儿期出现症状,儿童腹腔空间相对成人小,有更高的肠套叠风险。双气囊小肠镜(double-balloon enteroscopy,DBE)已被证实是一种安全有效的诊治小肠病变方法,但还需确定其预防性息肉切除治疗对PJS幼儿的疗效及安全性。回顾2018—2020年间被确诊为PJS的6例患儿(中位年龄10.6岁)资料,发现患儿中进行DBE治疗14次,其中3例患儿经DBE治疗成功解除肠套叠。切除的套叠息肉的大小分别为50 mm×60 mm,40 mm×35mm,50 mm×40 mm。所有患儿在DBE治疗后,与息肉相关的症状(腹部疼痛、肠套叠和阻塞)得到缓解。手术过程中未发现出血或穿孔等直接并发症,且随访未见肠套叠复发。可见,DBE息肉切除术治疗PJS引起的肠套叠安全有效。
Peutz-Jeghers syndrome(PJS)presents in early childhood,and children have a higher risk of intussusception due to a smaller abdominal space than adults.Double-balloon enteroscopy(DBE)has been proven to be a safe and effective method for the diagnosis and treatment of small bowel lesions,but the efficacy and safety of its prophylactic polypectomy in children with PJS need to be determined.Data of 6 children(median age 10.6 years)diagnosed as having PJS from 2018 to 2020 were reviewed.DBE was performed 14 times,and 3 children were successfully relieved of intussusception after DBE treatment.The sizes of the resected intussusception polyps were 50 mm×60 mm,40 mm×35 mm,and 50 mm×40 mm.Symptoms associated with polyps(abdominal pain,intussusception and obstruction)relieved after DBE in all children.No direct complications such as bleeding or perforation were found during the operation,and no recurrence of intussusception was found during follow-up.It can be seen that DBE polypectomy is safe and effective in the treatment of intussusception caused by PJS.
作者
朱珍妮
王明芳
王凤革
刘沁
舒蒙
伍代琴
胡赤军
Zhu Zhenni;Wang Mingfang;Wang Fengge;Liu Qin;Shu Meng;Wu Daiqin;Hu Chijun(Department of Child Gastroenterology,Maternity and Child Health Care Hospital of Hubei Province,Women and Children's Hospital of Hubei Province,Wuhan 430070,China;Department of Ultrasonic Diagnosis,Maternal and Child Health Hospital of Hubei Province,Women and Children's Hospital of Hubei Province,Wuhan 430070,China)
出处
《中华消化内镜杂志》
CSCD
2022年第4期322-325,共4页
Chinese Journal of Digestive Endoscopy
