摘要
目的 分析沈阳市高尿酸血症(HUA)检出率及其相关危险因素,进一步为该地区HUA的防治提供依据。方法 选取2013年1月至2020年12月在中国医科大学附属盛京医院进行健康体检的98 327例受检者的体检资料,分析HUA检出率情况,利用多因素logistic回归分析,统计HUA的危险因素。结果 HUA总体检出率为22.48%,男性HUA检出率为30.75%,女性为9.13%。男性检出率明显高于女性(P<0.05),检出率呈逐年递增的趋势。随着年龄的增长,男性HUA的检出率呈下降趋势,而女性40~59岁小幅下降,60岁后显著升高。随着体重指数(BMI)增高,HUA检出率也随之增高,且差异有统计学意义(P<0.05)。logistic回归分析显示,男性、体重指数、体检年度、高血压、高脂血症、高糖血症、甘油三脂、LDL-C、肝功异常、肾功异常与HUA呈正相关,年龄、HDL-C与HUA呈负相关。结论 沈阳市体检人群HUA以男性为主,随着BMI增高,HUA也随之增高。
Objective To analyze the prevalence and risk factors of hyperuricemia(HUA) in Shenyang City, and to provide evidence for the prevention and treatment of HUA in this region. Methods From January 2013 to December 2020,98 327 subjects who underwent physical examination in Shengjing Hospital of China Medical University in Shenyang were selected.The detection rate of HUA was calculated, and the risk factors of HUA were analyzed by multivariate logistic regression analysis. Results From 2013 to 2020,the overall prevalence of HUA was 22.48%,30.75% in males and 9.13% in females.The prevalence rate in the male was significantly higher than that in the female(P<0.05).Except for a slight decrease in 2015 and 2020,the total prevalence rate showed an increasing trend year by year.With the increase of age, the prevalence of HUA in males decreased, while in females, it decreased slightly from 40 to 59 years old and increased significantly after 60 years old.With the increase of BMI(Body Mass Index),the prevalence of HUA also increased, and the difference was statistically significant(P<0.05).Logistic regression analysis showed that male, body mass index, physical examination year, hypertension, hyperlipidemia, hyperglycemia, triglyceride, LDL-C,abnormal liver and renal function were positively correlated with HUA,while age and HDL-C were negatively correlated with HUA. Conclusion HUA occurs mainly in male people among physical examination population in Shenyang.With the increase of BMI,HUA increases.
作者
张亮
裴冬梅
ZHANG Liang;PEI Dong-mei(Department of Social Service,Shengjing Hospital of China Medical University,Shenyang,Liaoning 110004,China)
出处
《公共卫生与预防医学》
2022年第3期90-93,共4页
Journal of Public Health and Preventive Medicine
基金
美国中华基金会CMB(China Medical Board)项目(15-219)
辽宁省社会科学规划基金项目(L19BGL041)。
关键词
高尿酸血症
体检人群
检出率
危险因素
Hyperuricemia
Health examination population
Prevalence
Risk factors
