摘要
目的研究维生素D联合硫酸镁治疗妊娠期高血压对母婴结局的影响。方法选择2018年1月至2021年10月我院收治的妊娠期高血压患者150例,随机分为对照组(75例,硫酸镁)、联治组(75例,维生素D联合硫酸镁)。比较两组的血压、全血黏度、血细胞比容、脐动脉阻力指数、母婴不良结局、不良反应。结果治疗后,联治组的收缩压、舒张压低于对照组(P<0.05)。治疗后,联治组的血细胞比容、全血黏度及脐动脉阻力指数低于对照组(P<0.05)。联治组母婴不良结局发生率低于对照组(P<0.05)。两组的不良反应发生率比较无统计学差异(P>0.05)。结论维生素D联合硫酸镁治疗妊娠期高血压可显著降低患者的血压,改善母婴结局,安全性较高。
Objective To study the influence of vitamin D combined with magnesium sulfate on maternal and infant outcomes in the treatment of gestational hypertension.Methods 150 patients with gestational hypertension admitted to our hospital from January 2018 to October 2021 were selected and randomly divided into control group(75 cases,magnesium sulfate)and combined group(75 cases,vitamin D combined with magnesium sulfate).The blood pressure,whole blood viscosity,hematocrit,umbilical artery resistance index,adverse maternal and infant outcomes and adverse reaction were compared between the two groups.Results After treatment,the systolic blood pressure and diastolic blood pressure of the combined group were lower than those of the control group(P<0.05).After treatment,the hematocrit,whole blood viscosity and umbilical artery resistance index of the combined group were lower than those of the control group(P<0.05).The incidence of maternal and infant adverse outcomes in the combined group was lower than that in the control group(P<0.05).No statistical difference was found in the incidence of adverse reactions between the two groups(P>0.05).Conclusions Vitamin D combined with magnesium sulfate in the treatment of gestational hypertension can significantly reduce the blood pressure of patients,and improve the maternal and infant outcomes,with higher safety.
作者
杨颖
毕晶晶
李辞妹
YANG Ying;BI Jingjing;LI Cimei(Department of Obstetrics,Xinxiang Central Hospital/the Fourth Clinical College of Xinxiang Medical College,Xinxiang 453000,China)
出处
《临床医学工程》
2022年第5期659-660,共2页
Clinical Medicine & Engineering
关键词
维生素D
硫酸镁
妊娠期高血压
Vitamin D
Magnesium sulfate
Gestational hypertension
