摘要
目的:探讨T_(2)WI、DWI对鉴别局灶性自身免疫性胰腺炎(f-AIP)与胰腺癌(PC)的诊断价值。方法:回顾性分析10例f-AIP患者及20例PC患者的临床资料,并随机选取20例胰腺正常者(NP)的临床资料作为对照。分析其影像学特征,并测量T_(2)WI信号强度(SI)值、表观弥散系数(ADC)值进行统计学分析。结果:增强扫描动脉期、延迟期,f-AIP组与PC组病灶的信号特征差异有统计学意义(P<0.05);PC组T_(2)WI SI值为(0.431±0.036)×10^(-3),f-AIP组T_(2)WI SI值为(0.359±0.034)×10^(-3),NP组T_(2)WI SI值为(0.317±0.041)×10^(-3);两两比较差异有统计学意义(P<0.05)。根据受试者工作特征曲线(ROC),T_(2)WI SI鉴别f-AIP与PC最佳临界值为0.408×10^(-3),相应的敏感性为80.0%,特异性为90.0%,曲线下面积(AUC)为0.920。PC组ADC值为(1.082±0.107)×10^(-3)mm^(2)/s,f-AIP组ADC值为(0.979±0.053)×10^(-3)mm^(2)/s,NP组ADC值为(1.311±0.136)×10^(-3)mm^(2)/s;两两比较差异有统计学意义(P<0.05)。ADC鉴别f-AIP与PC最佳临界值为1.109×10^(-3)mm^(2)/s,相应的敏感性为60.0%,特异性为90.0%,AUC为0.813。两者联合诊断时的敏感性为92.0%,特异性为81.0%,AUC为0.953。结论:多参数MRI在f-AIP与PC的鉴别诊断中有一定价值。
Objective:To evaluate the diagnosis value of T_(2)WI and DWI in differentiating focal autoimmune pancreatitis(fAIP)from pancreatic cancer(PC).Methods:The clinical data of 10 patients with f-AIP and 20 patients with PC were analyzed retrospectively,and the clinical data of 20 patients with normal pancreas(NP)were randomly selected as controls.The imaging features were analyzed,and the signal intensity(T_(2)WI SI)of T_(2)WI and the apparent diffusion coefficient(ADC)were measured for statistical analysis.Results:There was significant difference in signal characteristics between f-AIP group and PC group in arterial phase and delayed phase(P<0.05).The T_(2)WI SI value of PC group was(0.431±0.036)×10^(-3),the T_(2)WI SI value of f-AIP group was(0.359±0.034)×10^(-3),and the T_(2)WI SI value of the NP group was(0.317±0.041)×10^(-3).There was significant difference between the two groups.According to the receiver operating characteristic(ROC)curve,the best critical value of T_(2)WI SI for the differential diagnosis between f-AIP and PC was 0.408×10^(-3),and the corresponding sensitivity and specificity were 80.0%and 90.0%,the area under curve(AUC)was 0.920.The ADC value of the PC group was(1.082±0.107)×10^(-3)mm^(2)/s,and the ADC value of the f-AIP group was(0.979±0.053)×10^(-3)mm^(2)/s,and the ADC value of the NP group was(1.311±0.136)×10^(-3)mm^(2)/s.There was statistical significant difference between the two groups(P<0.05).The best critical value of ADC for the differential diagnosis between f-AIP and PC was 1.109×10^(-3)mm^(2)/s,and the corresponding sensitivity and specificity are 60.0%and 90.0%,the AUC was 0.813.The sensitivity and specificity of the combined diagnosis were 92.0%and81.0%,the AUC was 0.953.Conclusion:Multi-parameter MRI has certain value in the differential diagnosis of f-AIP and PC.
作者
殷灿
邓喜青
YIN Can;DENG Xi-qing(Medical Imaging Center,Zhuzhou Hospital Affiliated to Xiangya School of Medicine,Central South University,Zhuzhou Hunan 412000,China)
出处
《中国临床医学影像杂志》
CAS
CSCD
2022年第3期189-192,共4页
Journal of China Clinic Medical Imaging
基金
株洲市卫生人才135工程重点科研项目(202005)。
关键词
胰腺炎
胰腺肿瘤
磁共振成像
Pancreatitis
Pancreatic Neoplasms
Magnetic Resonance Imaging
