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用伊立替康联合雷替曲塞对晚期胃癌患者进行三线化疗的效果观察

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摘要 目的:探讨用伊立替康联合雷替曲塞对晚期胃癌患者进行三线化疗的临床效果和安全性。方法:对2019年1月至2020年12月期间玉林市红十字会医院收治的35例晚期胃癌患者(经一线、二线化疗失败)的临床资料进行回顾性分析。为这些患者均采用伊立替康联合雷替曲塞进行三线化疗,然后观察其治疗效果及不良反应的发生情况。结果:治疗后,35例患者治疗的有效率为17.14%(6/35),其疾病的控制率为48.57%(17/35),其中位无进展生存时间为3.5个月。这些患者出现的不良反应包括血红蛋白下降、白细胞下降、血小板下降、恶心呕吐、腹泻、乏力等,多数患者的不良反应为Ⅰ~Ⅱ级。结论:用伊立替康联合雷替曲塞对晚期胃癌患者进行三线化疗可取得较好的疗效,且安全性较高。
出处 《当代医药论丛》 2022年第9期120-122,共3页
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