摘要
目的探究鹿角型肾结石经皮肾镜联合输尿管软镜治疗的临床疗效。方法选取2019年1月至2021年1月本院收治的120例鹿角型肾结石患者作为研究对象,按照计算机随机分组方式分为对照组和观察组,各60例。对照组行经皮肾镜碎石取石术治疗,观察组行经皮肾镜联合输尿管软镜治疗。比较两组结石清除率、手术相关指标(术中出血量、术后出血量、住院时间、手术时间)、血清应激激素水平、血清炎症因子水平及并发症发生情况。结果观察组结石清除率低于对照组,差异有统计学意义(P<0.05)。观察组术中出血量、术后出血量均少于对照组,住院时间短于对照组,但手术时间长于对照组,差异均有统计学意义(P<0.05)。观察组血清促肾上腺皮质激素(ACTH)、肾上腺激素(AD)、去甲肾上腺素(NE)水平均低于对照组,差异均有统计学意义(P<0.05)。观察组C反应蛋白(CRP)、白细胞介素-10(IL-10)水平及全血白细胞计数(WBC)均低于对照组,差异有统计学意义(P<0.05)。观察组并发症总发生率低于对照组,差异有统计学意义(P<0.05)。结论鹿角型肾结石患者接受经皮肾镜联合输尿管软镜治疗效果显著,可有效提高结石清除率,应激反应和炎症反应较弱,可缩短住院时间,促进患者早日康复,且并发症发生率低,值得临床推广应用。
Objective To explore the curative effect of percutaneous nephroscope combined with flexible ureteroscopy in the treatment of staghorn kidney stones.Methods A total of 120 patients with staghorn kidney stones admitted to our hospital from January 2019 to January 2021 were selected as the research subjects,and they were divided into control group and observation group according to the computer random grouping method,with 60 cases in each group.The control group was treated with percutaneous nephrolithotomy,and the observation group was treated with percutaneous nephroscope combined with flexible ureteroscopy.The rate of stone clearance,operation related indicators(intraoperative bleeding,postoperative bleeding,hospital stay,operation time),serum stress hormone level,serum inflammatory factor level and complications were compared between the two groups.Results The rate of stone clearance in the observation group was lower than that in the control group,the difference was statistically significant(P<0.05).The amount of intraoperative bleeding,postoperative bleeding in the observation group were less than those of the control group,and hospital stay was shorter than that in the control group,but the operation time was longer than that in the control group,and the difference was statistically significant(P<0.05).The levels of serum adrenocorticotropic hormone(ACTH),adrenal hormone(AD)and norepinephrine(NE)in the observation group were lower than those of the control group,and the difference was statistically significant(P<0.05).The levels of C-reactive protein(CRP),interleukin-10(IL-10)and white blood cell count(WBC)in the observation group were lower than those in the control group,and the difference was statistically significant(P<0.05).The incidence of complications in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion Percutaneous nephrolithiasis combined with flexible ureteroscopy is time-effective for patients with staghorn kidney sto
作者
陆荣森
梁华良
黄广龙
黄芳伟
梁多
LU Rongsen;LIANG Hualiang;HUANG Guanglong;HUANG Fangwei;LIANG Duo(Department of Urology,Xinyi People's Hospital,Maoming,Guangdong,535200,China)
出处
《当代医学》
2022年第13期32-35,共4页
Contemporary Medicine
