摘要
目的:探讨在无痛分娩中盐酸罗哌卡因与舒芬太尼硬膜外麻醉联合应用的临床价值。方法:选取2020年1月-2021年1月景德镇市妇幼保健院产科接收的118例待分娩产妇为研究对象,随机分为研究组和对照组,每组59例。对照组采用盐酸罗哌卡因麻醉,研究组采取盐酸罗哌卡因与舒芬太尼联合的硬膜外麻醉。比较两组麻醉效果、镇痛指标、分娩情况及不同时间一氧化氮与皮质醇水平。结果:与对照组比较,研究组麻醉优良率相对较高(P<0.05)。与对照组比较,研究组镇痛起效与完全阻滞用时均较少,而镇痛持续时间则较长(P<0.05)。与对照组比较,研究组第一产程用时较少(P<0.05),而两组胎心率、第二产程时间与1、5 min Apgar评分比较,差异均无统计学意义(P>0.05)。与对照组比较,研究组镇痛1 h后及新生儿娩出后NO指标均较高,而皮质醇水平均较低(P<0.05)。结论:在无痛分娩中采用盐酸罗哌卡因与舒芬太尼硬膜外麻醉,能获得较好的麻醉及镇痛效果,缩短产程时间,改善其一氧化氮与皮质醇水平,利于母婴安全,值得临床推广应用。
Objective:To explore the clinical value of combined Ropivacaine Hydrochloride and Sufentanil epidural anesthesia in painless labor.Method:A total of 118 pregnant women waiting for delivery in the Obstetrics Department of Jingdezhen Maternal and Child Health Hospital from January 2020 to January 2021 were selected as the research objects,and they were randomly divided into the study group and the control group,59 cases in each group.The control group was anesthetized with Ropivacaine Hydrochloride alone,and the study group was anesthetized with Ropivacaine Hydrochloride and Sufentanil combined with epidural anesthesia.The effects of anesthesia,analgesia indicators,delivery conditions and the levels of nitric oxide and cortisol at different times were compared between two groups.Result:Compared with the control group,the excellent and good rate of anesthesia in the study group was relatively higher (P<0.05).Compared with the control group,the onset and complete block time of analgesia in the study group were less,while the duration of analgesia was longer (P<0.05).Compared with the control group,the time of the first stage of labor of study group was less (P<0.05),but there were no significant differences between two groups in fetal heart rate,the time of the second stage of labor and Apgar score at1 and 5 min (P>0.05).Compared with the control group,the NO indexes were higher after 1 h of analgesia and after newborn delivered,while the cortisol level was lower (P<0.05).Conclusion:The use of Ropivacaine Hydrochloride and Sufentanil for epidural anesthesia in painless labor can achieve better anesthesia and analgesia,shorten the time of maternal labor,improve the concentration of nitric oxide and cortisol,it is beneficial to the safety of mothers and infants and is worthy of clinical application.
作者
汪志飞
任海雪
WANG Zhifei;REN Haixue(Jingdezhen Maternal and Child Health Hospital,Jiangxi Province,Jingdezhen 333000,China;不详)
出处
《中国医学创新》
CAS
2022年第8期151-154,共4页
Medical Innovation of China
关键词
无痛分娩
盐酸罗哌卡因
舒芬太尼
硬膜外麻醉
Painless labor
Ropivacaine Hydrochloride
Sufentanil
Epidural anesthesia
