摘要
目的探讨广泛性焦虑障碍(General anxiety disorder,GAD)患者在风险明确情境下的决策功能。方法采用骰子博弈测试(Game of dice test,GDT)评估首次诊断为GAD的21例患者及性别、年龄、受教育年限相匹配的20例健康对照者风险明确情境下的决策功能,同时进行神经心理学量表测评。结果GAD组风险选项次数(4.14±2.61)与健康对照组(6.55±4.56)比较有明显差异(t=-2.087,P<0.05);GAD组非风险选项次数(13.86±2.61)与健康对照组(11.45±4.56)比较也存在明显差异(t=2.087,P<0.05);2组负反馈利用率无明显差异(P>0.05);GAD组数字符号编码测验(Symbol digit modalities,SDMT)测验成绩(49.29±17.85)明显较健康对照组(59.4±17.67)差(z=-1.971,P=0.049)。结论GAD患者在风险明确情境下决策更倾向于风险规避,且对负面损失的敏感度与健康对照组比较无明显差异;GAD患者注意力和信息处理速度能力较健康个体差。
Objective To investigate the decision-making function of patients with generalized anxiety disorder(GAD) under clear risk situations.Methods The Game of Dice Test(GDT) was used to evaluate the decision-making function of 21 patients first diagnosed with GAD and 20 healthy controls matched by gender, age and years of education under the risk explicit situation, and the neuropsychological scale was also used to evaluate the cognition.Results There was statistical difference in the number of risk options between GAD group(4.14±2.61) and healthy control group(6.55±4.56)(t=-2.087, P<0.05).There was also significant difference in the number of non-risk options between the GAD group(13.86±2.61) and the healthy control group(11.45±4.56)(t=2.087, P<0.05).There was no significant difference in utilization of negative feedback between the two groups(P>0.05).The SDMT score of GAD group(49.29±17.85) was lower than that of control group(59.4±17.67), and the difference was statistically significant(z=-1.971, P=0.049).Conclusion GAD patients were more prone to risk avoidance when the risk was clear, and their sensitivity to negative loss was not significantly different from that of healthy controls. GAD patients have lower attention and information processing speed capabilities than healthy individuals.
作者
胡盼
毛善平
Hu Pan;Mao Shan-ping(Department of Neurology,Renmin Hospital of Wuhan University,Wuhan 430060)
出处
《卒中与神经疾病》
2022年第2期160-163,共4页
Stroke and Nervous Diseases
关键词
广泛性焦虑障碍
风险决策
骰子博弈测试
神经心理
Generalized anxiety disorder
Risk decision
Dice game test
Neuropsychological
