摘要
目的探讨超声造影在子宫内膜恶性病变诊断中的价值。方法选取2019年1月至2021年9月于首都医科大学附属北京天坛医院行超声造影检查的子宫内膜病变患者142例,以术后病理为金标准,将患者分为良性组(包括子宫内膜增生及子宫内膜息肉)和恶性组(子宫内膜癌),比较良性组与恶性组造影增强模式的差异。以早增强或同步增强或早达峰为诊断子宫内膜恶性病变的指标,计算超声造影诊断子宫内膜恶性病变及病变厚度≥10 mm子宫内膜恶性病变的敏感性、特异性、总符合率并计算Kappa值。结果共有108例患者进行了手术且有明确的病理结果,其中良性组66例,恶性组42例。恶性组病变厚度大于良性组,差异有统计学意义(t=4.039,P<0.05),但两组病变血流动力学参数差异无统计学意义(P>0.05)。恶性组超声造影开始增强时间、达峰时间、峰值强度与良性组差异有统计学意义(均P<0.05)。超声造影诊断子宫内膜恶性病变的敏感性为64.3%,特异性为100%,Kappa值为0.688。超声造影诊断病变厚度≥10 mm子宫内膜恶性病变的敏感性为75.0%,特异性为100%,Kappa值为0.795。结论对于子宫内膜恶性病变,尤其是厚度≥10 mm子宫内膜恶性病变的诊断中,超声造影具有较高的诊断符合率,早增强或同步增强或早达峰为子宫内膜恶性病变较为特异的超声造影表现。
Objective To investigate the value of contrast-enhanced ultrasound(CEUS)in the diagnosis of malignant endometrial lesions.Methods A total of 142 patients with endometrial lesions who underwent contrast-enhanced ultrasound examination in Beijing Tiantan Hospital,Capital Medical University from January 2019 to September 2021 were selected.The endometrial lesions were divided into benign group(including endometrial hyperplasia and endometrial polyps)and malignant group(endometrial cancer)according to the pathological results of surgery,and the differences of contrast enhancement patterns between benign group and malignant group were compared.The sensitivity,specificity of CEUS in the diagnosis of endometrial cancer were calculated,and the Kappa value was calculated with the initial enhancement time earlier than or equal to the muscularity or the peak time earlier than the muscularity as the diagnostic index for the diagnosis of endometrial malignant lesions.The sensitivity,specificity,and Kappa value of CEUS in the diagnosis of endometrial cancer and endometrial cancer with thickness≥10 mm were calculated.Results A total of 108 patients underwent surgery with clear pathological results,including 66 patients in the benign lesion group and 42 patients in the malignant lesion group.The thickness of malignant lesions was significantly larger than that of benign lesions,and the difference was statistically significant(t=4.039,P<0.05),but there was no significant difference of hemodynamic parameters between the two groups(P>0.05).The initial enhancement time,peak time and peak intensity of benign lesions were significantly different from those of malignant lesions(all P<0.05).The sensitivity,specificity,and Kappa value of CEUS in the diagnosis of endometrial cancer were 64.3%,100%and 0.668,respectively.The sensitivity,specificity and Kappa value of CEUS in the diagnosis of endometrial carcinoma with lesion thickness≥10 mm were 75.0%,100%and 0.795,respectively.Conclusions For the diagnosis of endometrial lesions,especi
作者
王立淑
于腾飞
徐云
张红霞
刘影
宋海曼
何文
Wang Lishu;Yu Tengfei;Xu Yun;Zhang Hongxia;Liu Ying;Song Haiman;He Wen(Department of Ultrasound,Beijing Tiantan Hospital,Capital Medical University,Beijing 100070,China;Department of Obestetrics and Gynecology,Beijing Tiantan Hospital,Capital Medical University,Beijing 100070,China)
出处
《中华超声影像学杂志》
CSCD
北大核心
2022年第3期226-230,共5页
Chinese Journal of Ultrasonography
关键词
超声造影
子宫内膜病变
子宫内膜癌
Contrast-enhanced ultrasound
Endometrial lesions
Endometrial cancer
