摘要
目的:运用证素理论证实腹泻型肠易激综合征(IBS-D)的发病与心小肠藏象系统密切相关及心小肠藏象系统致病病机主要表现为心阳不足,从而为从心小肠藏象系统论治IBS-D这一治疗思路提供直观可靠的理论依据。方法:对我院门诊及住院120例IBS-D患者进行四诊信息的采集,将相关四诊信息录入证素分析软件得出病位和病性证素积分,提取主要病位小肠证素组,运用SPSS软件进行双变量相关分析以探讨病位小肠与心等其他病位证素的相关性,若病位证素小肠与心两者具有相关性,则从小肠证素组中提取出心证素组,再运用SPSS软件进行双变量相关分析以探讨病位心与病性证素的相关性。结果:120例IBS-D患者的常见病位证素出现的频数从高往低的分布情况:小肠>脾>肝>心>大肠>胆>肾>胃>心神;病性证素出现的频数从高往低的分布情况:阳虚>气虚>湿>气滞>痰>寒>血虚>血瘀>阴虚>热;从120例IBS-D患者中提取主要病位小肠证素组(112例),病位小肠与心等其他病位证素的相关系数从高到低依次为:脾>肝>大肠>心,表明小肠与脾、肝、大肠、心存在显著的相关性(P<0.05),与胃、胆、肾、心神不存在相关性(P>0.05);从112例小肠证素组IBS-D患者中提取病位心证素组(90例),病位心与病性证素的相关系数从高到低依次为:阳虚>痰>湿>气虚>气滞,表明心与阳虚、痰、湿、气虚、气滞存在显著的相关性(P<0.05),与血瘀、阴虚、血虚、寒、热不存在相关性(P>0.05)。结论:IBS-D的发病关键在于心小肠藏象系统功能失常,病机为心阳不足,小肠失于温煦,泌别清浊失司,并与脾、肝、大肠等脏腑密切相关,临床属虚实夹杂病证,并多见虚多实少,郁而化热,为寒多热少,标实可兼见痰、湿、气滞、湿热、食滞、寒凝、血瘀等,而主体病证在心小肠藏象系统,说明了从心小肠藏象系统论治IBS-D是有必要的,可行的,有效的,提供�
Objective:To confirm the pathogenesis of diarrhea-type irritable bowel syndrome(IBS-D)is closely related to the heart and small intestine Tibetan system,and the pathogenesis of the heart and small intestine system is mainly manifested in deficiency of heart yang by using the theory of syndrome elements.The treatment idea of IBS-D based on the system of the heart and the small intestine can provide an intuitive and reliable theoretical basis.Methods:Collect the information of the four diagnoses from 120 IBS-D patients in our hospital and inpatients,enter the relevant information of the four diagnoses into the syndrome element analysis software to obtain the disease location and disease syndrome score,and extract the small intestine syndrome element group of the main disease location.,using SPSS software to carry out bivariate correlation analysis to explore the correlation between the disease location of the small intestine and other disease sites such as the heart,if there is a correlation between the disease location of the small intestine and the heart,the heart is extracted from the small intestine syndrome group.Syndrome element group,and then use SPSS software to conduct bivariate correlation analysis to explore the correlation between disease location heart and disease syndrome element.RESULTS:The frequency distribution of common disease-site syndrome elements in 120 IBS-D patients from high to low:small intestine>spleen>liver>heart>large intestine>biliary>kidney>stomach>Xinshen;frequency of disease-related syndromes The distribut ion from high to low:yang deficiency>Qi deficiency>dampness>Qi stagnation>phlegm>cold>blood deficiency>blood stasis>yin deficiency>heat;from 120 patients with IBS-D,the main disease group small intestine syndrome group(112 cases),the correlation coefficients of the disease site small intestine and other disease sites such as the heart are from high to low:spleen>liver>large intestine>heart,indicating that there is a significant correlation between the small intestine and the splee
作者
邱健
李连勇
叶凡
许赋瑜
QIU Jian;LI Lianyong;YE Fan;XU Fuyu(Fuding Hospital Affiliated of Fujian University of Traditional Chinese Medicine Fujian Fuzhou 355200,China)
出处
《中医药临床杂志》
2022年第3期534-538,共5页
Clinical Journal of Traditional Chinese Medicine
基金
国家中医药管理局全国基层名老中医药专家传承工作室建设项目
福建中医药大学2019年校管课题中医脾胃学科开放课题(项目编号:X2019015-学科)。
关键词
腹泻型肠易激综合征
证素
心小肠藏象系统
心阳不足
理论依据
Irritable Bowel Syndrome-Diarrhea
Syndrome elements
Heart and small intestine’s viscera system
Yang deficiency of the heart
Theoretical basis
