期刊文献+

艾灸辅助艾速康对HIV/AIDS患者疗效及miR-222、血清CD4^(+)的影响 被引量:1

Influence of Moxibustion Assisted with Aisukang on the Curative Effect and miR-222and serum CD4^(+)of HIV/AIDS Patients
下载PDF
导出
摘要 目的探究艾灸辅助艾速康对获得性免疫缺陷综合征(HIV/AIDS)患者疗效及miR-222、辅助T淋巴细胞(血清CD4^(+))的影响。方法选取在郑州市第六人民医院治疗的HIV/AIDS患者120例随机分为参考组(60例)和观察组(60例)。其中参考组在一线抗病毒方案的基础上加用艾速康口服液治疗,观察组在参考组的基础上给予艾灸辅助治疗。比较2组患者血清CD4^(+)、miR-222水平,临床疗效,症状积分变化情况。结果与治疗前比较,2组治疗后血清CD4^(+)水平均明显升高(P<0.05),且与参考组比较,观察组明显升高(P<0.05);2组miR-222水平及神疲懒言、烦躁易怒、口干口苦、食欲不振、脘闷腹胀、倦怠无力、腰膝酸软等症状评分明显降低(P<0.05),且与参考组比较,观察组明显降低(P<0.05);与参考组总有效率78.33%比较,观察组93.33%明显升高(P<0.05)。结论HIV/AIDS患者使用艾灸辅助艾速康治疗可有效提高血清CD4^(+)水平,降低miR-222水平,改善患者临床症状,提高患者免疫功能,疗效显著。 Objective To explore the curative effect of moxibustion assisted with Aisukang on patients with acquired immunodeficiency syndrome(HIV/AIDS)and the influences on miR-222 and helper T lymphocyte(serum CD4^(+)).Methods A total of 120 cases of HIV/AIDS patients treated in Zhengzhou Sixth People’s Hospital were randomly divided into control group(60 cases)and observation group(60cases).The control group was treated with Aisukang oral liquid on the basis of the first-line antiviral program,and the observation group was treated with moxibustion on the basis of the control group.The levels of serum CD4 and miR-222,clinical efficacy and symptom score were compared between the two groups.Results Compared with before treatment,the level of serum CD4^(+)in the two groups were significantly increased after treatment(P<0.05),and compared with the control group,the levels of serum CD4^(+)in the observation group were significantly increased(P<0.05).The level of miR-222 and symptom scores of mental fatigue and laziness to speak,irritability,dry and bitter mouth,loss of appetite,abdominal distension,fatigue and weakness,and soreness of waist and knee were significantly lower in the two groups(P<0.05),and the observation group was significantly lower than the control group(P<0.05).Compared with 78.33%in the control group,the total effective rate of 93.33%in the observation group was significantly higher(P<0.05).Conclusion Moxibustion assisted with Aisukang can effectively improve the level of serum CD4^(+),reduce the level of miR-222,and improve the clinical symptoms and immune function of patients with HIV/AIDS,with remarkable effect.
作者 张焕霞 刘春礼 孙晓明 崔美灵 焦敏 仝小庆 孙燕 ZHANG Huanxia;LIU Chunli;SUN Xiaoming;CUI Meiling;JIAO Min;TONG Xiaoqing;SUN Yan(Department of Infection,Zhengzhou Sixth People’s Hospital,Henan Province,Zhengzhou 450000,China)
出处 《光明中医》 2022年第5期840-843,共4页 GUANGMING JOURNAL OF CHINESE MEDICINE
基金 河南省医学科技攻关计划项目(No.2018020851) 河南省科技攻关计划项目(No.152102310178) 河南省中医药科学研究专项课题(No.2018ZY3021)。
关键词 艾速康 艾灸疗法 获得性免疫缺陷综合征 Aisukang moxibustion therapy acquired immunodeficiency syndrome
  • 引文网络
  • 相关文献

参考文献8

二级参考文献58

共引文献261

同被引文献15

引证文献1

;
使用帮助 返回顶部