摘要
上皮样滋养细胞肿瘤(epithelioid trophoblastic tumor,ETT)是一种来源于绒毛膜羊膜型中间滋养细胞的恶性肿瘤。ETT常与前次妊娠史有关,多数继发于前次正常妊娠,而继发于妊娠滋养细胞肿瘤(gestational trophoblastic neoplasia,GTN)的ETT患者非常罕见。报告1例继发于前次葡萄胎的ETT患者,曾因葡萄胎行清宫术,2年后因子宫异常出血行宫腔镜手术时发现该疾病,考虑为ETT伴可疑肺转移。患者经子宫切除手术和辅助化疗后预后较好。现结合相关个案报道,总结该类ETT的发病时间、部位等临床表现,超声、病理和免疫组织化学特点,治疗方案及预后,以提高临床医师对ETT的认识,改善ETT的治疗方式及预后。
Epithelioid trophoblastic tumor(ETT)is a malignant tumor derived from chorioamniotic intermediate trophoblast.ETT is often related to the previous pregnancy history,most of which are secondary to the previous normal pregnancy,while ETT patients who are secondary to gestational trophoblastic neoplasia(GTN)are very rare.A patient with ETT secondary to the previous hydatidiform mole underwent uterine curettage because of hydatidiform mole,and hysteroscopic surgery was performed 2 years later because of abnormal uterine bleeding.The disease was found and was considered as ETT with suspected lung metastasis.The prognosis of the patients was good after hysterectomy and adjuvant chemotherapy.Combined with related case reports,the clinical features,such as onset time,location,ultrasound,pathology and immunohistochemistry,treatment and prognosis of this kind of ETT were summarized in order to improve clinicians′understanding of the disease and make efforts to improve the treatment and prognosis of the disease.
作者
邱世康
姜慧慧
李长忠
邹永辉
QIU Shi-kang;JIANG Hui-hui;LI Chang-zhong;ZOU Yong-hui(Shandong University,Jinan 250012,China;Qingdao Medical College of Qingdao University,Qingdao 266000,Shandong Province,China;Department of Gynecology,Provincial Hospital Affiliated to Shandong University,Jinan 250012,China)
出处
《国际妇产科学杂志》
CAS
2022年第2期233-237,共5页
Journal of International Obstetrics and Gynecology
关键词
子宫肿瘤
滋养层肿瘤
诊断
治疗
预后
病例报告
上皮样滋养细胞肿瘤
Uterine neoplasms
Trophoblastic neoplasms
Diagnosis
Therapy
Prognosis
Case reports
Epithelioid trophoblastic tumor
