摘要
目的:比较3D腹腔镜与开腹Glisson蒂横断式肝切除术对肝细胞癌患者术后胃肠激素水平及氧化应激反应的影响。方法:将80例肝细胞癌患者按照随机数字表法分组,对照组40例给予开腹Glisson蒂横断式肝切除术,观察组40例给予3D腹腔镜Glisson蒂横断式肝切除术。观察两组术后恢复情况、胃肠激素水平氧化应激反应及并发症情况。结果:观察组术后肛门排气、进食、排便、拔管时间比对照组短,观察组术后1 d VAS评分比对照组低(P<0.05);术后,观察组GAS、MTL比对照组高,观察组CCK比对照组低(P<0.05);术后,观察组MDA、AOPP比对照组低,观察组SOD水平比对照组高(P<0.05);术后,观察组并发症发生率5.0%比对照组22.5%低(P<0.05)。结论:3D腹腔镜可改善开腹Glisson蒂横断式肝切除术伴肝细胞癌患者胃肠激素水平,减轻氧化应激反应,促进术后恢复,减少术后并发症发生。
Objective:To compare the effects of 3 D laparoscopic and open Glisson pedicle transection hepatectomy on the postoperative gastrointestinal hormone levels and oxidative stress in patients with hepatocellular carcinoma.Methods:80 patients with hepatocellular carcinoma were randomized into two groups.40 patients in the control group were treated with open Glisson pedicle transection hepatectomy,while another 40 patients in the observation group were treated with 3 D laparoscopic Glisson pedicle transection hepatectomy.The postoperative recovery,gastrointestinal hormone levels,oxidative stress and complications were compared between the two groups.Results:The time of anal exhaust,food-intaking,defecation and extubation in the observation group was shorter than that in the control group,and the VAS score 1 day after operation was lower than that in the control group(P<0.05);GAS and MTL in the observation group was higher than that in the control group,and CCK was lower than that in the control group(P<0.05);MDA and AOPP in the observation group was lower than that in the control group,and the level of SOD was higher than that in the control group(P<0.05);and the incidence of complications in the observation group was 5.0%,lower than 22.5%in the control group(P<0.05).Conclusion:3 D laparoscopy can improve the level of gastrointestinal hormones in patients with hepatocellular carcinoma undergoing open Glisson pedicle transection hepatectomy,diminish oxidative stress,promote postoperative recovery,and reduce postoperative complications.
作者
罗红杰
黄运德
王万鹏
LUO Hongjie;HUANG Yunde;WANG Wanpeng(Dept.of Hepatobiliary&Pancreatic Minimally Invasive Surgery,the Affiliated Zhengzhou Central Hospital of Zhengzhou University,Zhengzhou 450000,China)
出处
《华夏医学》
CAS
2022年第1期31-35,共5页
Acta Medicinae Sinica
