摘要
目的分析新疆医科大学附属肿瘤医院2015~2019年收治的新发8170例女性乳腺癌患者的生存情况,为改善乳腺癌预后提供依据。方法对2015-2019年8170例新发女性乳腺癌患者进行随访,随访时间截至2020年12月14日。采用寿命表法计算观察生存率,比较不同年龄组、不同肿瘤分期的乳腺癌患者整体生存情况。结果8170例乳腺癌患者中,有效随访人数7804例,随访率为95.52%。1年、2年、3年和5年生存率分别为96.0%、92.0%、89.0%、85.0%。随着发病年龄增加,1年、2年、3年和5年生存率均呈下降趋势,但35岁以下患者的生存率也较低,年龄组间生存率差异有统计学意义(P<0.01)。随着肿瘤分期的进展,乳腺癌患者的生存率呈显著下降趋势,Ⅰ、Ⅱ期患者的生存率明显高于Ⅲ、Ⅳ期,差异有统计学意义(P<0.01)。结论乳腺癌患者的生存率与年龄及肿瘤分期密切相关,应通过加强乳腺癌防治科普宣教及早诊早治工作,有效提高生存期,降低死亡率。
Objective To study the survival status of 8170 female breast cancer patients.Methods A total of 8170 female breast cancer patients from 2015-2019 years were observed and followed up.All patients were followed up until December 14,2020.The observed survival rate were estimated by the life tables method with log-rank test for the detection of observed differences across age and tumor staging group.Results Among 8,170 breast cancer patients,there were 7804 cases of effective follow-up,and the follow-up rate was 95.52%.The 1-year,2-year,3-year,and 5-year cumulative survival rates were 96.0%,92.0%,89.0%,and 85.0%,respectively.As the age of onset increases,the 1-year,2-year,3-year and 5-year survival rates all showed a downward trend,while the survival rates of patients under 35 years old and over 75 years old were relatively low.The difference showed statistical significance(P<0.01)among age groups.With the progression of tumor stage,the survival rate of breast cancer patients showed a significant downward trend.The survival rate for patients in stageⅠ,stageⅡwas significantly higher than those patients in stageⅢandⅣ,the difference was statistically significant(P<0.01).Conclusion The survival rate of breast cancer patients is closely related to age and tumor stage,so it is necessary to strengthen the popularization and education of breast cancer prevention and treatment as well as early diagnosis and treatment to effectively improve the survival time and reduce the mortality rate.
作者
刘新亚
曹明芹
LIU Xinya;CAO Mingqin(Affiliated Tumor Hospital of Xinjiang Medical University,Urumqi,830011)
出处
《实用癌症杂志》
2022年第4期659-663,共5页
The Practical Journal of Cancer
关键词
乳腺癌
随访
生存率
预后
Breast cancer
Follow up
Survival analysis
Prognosis
