摘要
【目的】观察醒脑开窍针刺法治疗脑梗死早期运动功能障碍的临床疗效。【方法】将96例早期脑梗死患者随机分为观察组和对照组,每组各48例。对照组给予常规治疗,观察组在对照组治疗的基础上,给予醒脑开窍针刺法治疗。连续治疗8周。治疗8周后,观察2组患者治疗前后美国国立卫生研究院卒中量表(NIHSS)评分与简化肢体运动功能评定量表(FMA)评分的变化情况,以及功能性步行量表(FAC)评分与Barthel指数(BI)评分的情况,比较2组患者治疗前后血清白细胞介素(IL)-6、IL-8、肿瘤坏死因子α(TNF-α)含量的变化情况,并采用表面肌电图检测肱二头肌、腕屈肌、股直肌、股二头肌的积分肌电值(iEMG)的变化情况。【结果】(1)治疗后,2组患者的NIHSS评分与BI指数评分均明显改善(P<0.05),且观察组在改善NIHSS评分与BI指数评分方面均明显优于对照组,差异均有统计学意义(P<0.05)。(2)治疗后,2组患者的FMA评分(包括上肢与下肢)及FAC评分均明显改善(P<0.05),且观察组在改善FMA评分(包括上肢与下肢)及FAC评分方面均明显优于对照组,差异均有统计学意义(P<0.05)。(3)治疗后,2组患者的IL-6、IL-8、TNF-α含量均明显改善(P<0.05),且观察组在改善IL-6、IL-8、TNF-α含量方面均明显优于对照组,差异均有统计学意义(P<0.05)。(4)治疗后,2组患者的肱二头肌、腕屈肌、股直肌、股二头肌iEMG值均明显改善(P<0.05),且观察组在改善肱二头肌、腕屈肌、股直肌、股二头肌iEMG值方面均明显优于对照组,差异均有统计学意义(P<0.05)。【结论】醒脑开窍针刺法治疗脑梗死早期运动功能障碍,能明显改善患者的运动功能,提高患者的生活质量,减轻氧化应激反应,疗效显著。
Objective To observe the clinical efficacy of Xingnao Kaiqiao Acupuncture therapy in the treatment of motor dysfunction in early cerebral infarction.Methods Ninety-six patients with early cerebral infarction were randomly divided into observation group and control group,with 48 cases in each group.The control group was given conventional treatment,and the observation group was given Xingnao Kaiqiao acupuncture treatment on the basis of the control group,and the treatment lasted for 8 continuous weeks.After 8 weeks of treatment,the changes of National Institutes of Health Stroke Scale(NIHSS)score,simplified limb motor function assessment scale(FMA)score,Functional Ambulation Category(FAC)score and Barthel index score in two groups were observed before and after treatment.The changes of serum interleukin(IL)-6,IL-8 and tumor necrosis factorα(TNF-α)levels were compared between two groups before and after treatment,and the changes of integrated electromyography(iEMG)of upper limbs(biceps brachii,flexor wrist)and lower limbs(rectus femoris,biceps femoris)were detected by surface electromyography.Results(1)After treatment,NIHSS score and BI index score of two groups were significantly improved(P<0.05),and the improvement of the observation group was significantly superior to that of the control group,the difference being statistically significant(P<0.05).(2)After treatment,FMA score(including upper and lower limbs)and FAC score in two groups were significantly improved(P<0.05),and the improvement of the observation group was significantly superior to that of the control group,the difference being statistically significant(P<0.05).(3)After treatment,the contents of IL-6,IL-8,TNF-αin two groups were significantly improved(P<0.05),and the improvement of the observation group was significantly superior to that of the control group,the difference being statistically significant(P<0.05).(4)After treatment,iEMG values of biceps brachii,flexor carpi,rectus femoris and biceps femoris in both groups were significantly improve
作者
冼丽霞
李润明
朱海丰
潘国坚
肖赛兰
伍广锐
XIAN Li-Xia;LI Run-Ming;ZHU Hai-Feng;PAN Guo-Jian;XIAO Sai-Lan;WU Guang-Rui(Nanhai Hospital of Guangdong Provincial People’s Hospital,Foshan 528000 Guangdong,China;Guangzhou Baiyunshan Baidi Biomedical Co.,Ltd.,Guangzhou 511495 Guangdong,China)
出处
《广州中医药大学学报》
CAS
2022年第4期831-836,共6页
Journal of Guangzhou University of Traditional Chinese Medicine
基金
佛山市卫生和计生局医学科研项目(编号:20190296)。
关键词
醒脑开窍针刺法
脑梗死
运动功能
生活质量
临床观察
Xingnao Kaiqiao acupuncture
cerebral infarction
motor function
quality of life
clinical observation
