摘要
目的建立献血者意外抗体常规筛查方法,分析血站集中开展献血者开展意外抗体筛查的结果,并与分散检测的成本进行比较。方法使用微柱凝胶法对2021年3月31日-2021年7月31日,35591名献血者开展意外抗体筛查,意外抗体筛查反应性标本由本中心输血研究所做进一步鉴别。通过对意外抗体阳性人群的分析,确定其人群特征。从直接成本和间接成本2方面,比较集中和分散完成献血者意外抗体筛查的支出。结果共计确认意外抗体阳性标本40例,深圳地区献血者意外抗体阳性率为0.11%(40/35591),意外抗体类型及占比:MNS系统的意外抗体占35%(14/40),Rh系统意外抗体占32.5%(13/40),Lewis系统意外抗体占17.5%(7/40)。意外抗体阳性献血者中男性占45%(18/40),女性占55%(22/40),具有显著性差异(P<0.01)。年龄、是否为重复献血者无显著性差异(P>0.05)。集中开展意外抗体筛查较分散检测模式,每年节省费用约116万元。结论有必要全面开展献血者意外抗体筛查工作,且集中较分散筛查的成本更低。
Objective To establish a routine screening method for unexpected antibodies of blood donors,analyze the results of centralized screening for unexpected antibody of blood donors in the blood center,and compare the cost of centralized and decentralized screening modes.Methods A total of 35591 blood donors were screened for unexpected antibodies from March 31,2021 to July 31,2021,using microcolumn gel method.Unexpected antibody screening reactive samples were further confirmed by the Transfusion Research Institute of Shenzhen Blood Center,and the demographic characteristics were further determined through the analysis of unexpected antibody positive population.The direct cost and indirect cost of centralized and decentralized unexpected antibody screening mode were compared.Results Forty unexpected antibody positive samples were confirmed in Shenzhen,with the positive rate at 0.11%(40/35591),among which MNS,Rh and Lewis system accounted for 35%(14/40),32.5%(13/40)and 17.5%(7/40),respectively.Males and females accounted for 45%(18/40)and 55%(22/40),respectively(P<0.01).No significant difference was noticed by age and repeated-donor or not(P>0.05).Unexpected antibody screening in a centralized way saved about 1.16 million yuan per year.Conclusion It is necessary to carry out unexpected antibody screening for all blood donors,and centralized screening is more economical than decentralized screening.
作者
黄力勤
邬林枫
李彤
李然
刘衡
杜丹丹
陈云龙
曾雪珍
曾劲峰
HUANG Liqin;WU Lifeng;LI Tong;LI Ran;LIU Heng;DU Dandan;CHEN Yunlong;ZENG Xuezheng;ZENG Jinfeng(Shenzhen Blood Centre,Shenzhen 518025,China)
出处
《中国输血杂志》
CAS
2022年第3期324-327,共4页
Chinese Journal of Blood Transfusion
基金
深圳市医疗卫生三名工程(SZSM201811092)
深圳市医学重点学科建设经费(SZXK070)
中国医学装备协会输血医学装备技术专业委员会血液筛查技术科研课题。
关键词
献血者
意外抗体
筛查
成本比较
blood donor
unexpected antibody
blood screening
cost comparison
