摘要
目的:对化痰祛瘀汤加减对急性脑梗死(ACI)患者神经功能康复及生活能力的影响进行探讨。方法:将119例ACI患者随机分为对照组(n=59)和观察组(n=60),对照组采用西医常规治疗,观察组在此基础上采用化痰祛瘀汤加减治疗,比较两组患者的疗效、神经功能以及生活能力的改善情况。结果:治疗后,观察组总有效率高于对照组(96.67%vs 86.44%,P<0.05);观察组神经功能缺损(NIHSS)评分、中医证候积分以及神经元特异性烯醇化酶(NSE)水平显著低于对照组,日常生活能力(ADL)评分、血清神经生长因子(NGF)和脑源性神经营养因子(BDNF)水平显著高于对照组(均P<0.05)。结论:化痰祛瘀汤加减对ACI疗效显著,可有效促进受损神经功能的修复,提高患者的生活能力。
Objective:To explore the effect of Huatan Quyu decoction on the rehabilitation of nerve function and life ability in patients with acute cerebral infarction(ACI).Methods:One hundred and nineteen patients with ACI were randomly divided into a control group(n=59)and an observation group(n=60).The control group was treated with routine Western medicine while the observation group with Huatan Quyu decoction besides routine Western medicine.The curative effect,nerve function and life ability were compared between the two groups.Results:After treatment,overall response rate in observation group was higher than that in control group(96.67%vs 86.44%,P<0.05).The neurological deficit score(NIHSS),TCM syndrome score and neuron-specific enolase(NSE)levels were significantly lower and the ADL,serum nerve growth factor(NGF)and brain-derived neurotrophic factor(BDNF)levels were significantly higher in the observation group than the control group(all P<0.05).Conclusion:Huatan Quyu decoction has significant curative effect on ACI,can promote the repair of damaged nerve function and improve the life ability of patients.
作者
李雪飞
陈颜嫣
王伟伟
LI Xuefei;CHEN Yanyan;WANG Weiwei(Department of Rehabilitation Medicine,He’nan No.3 Provincial People’s Hospital,Zhengzhou 450000,China)
出处
《上海医药》
CAS
2022年第7期31-34,共4页
Shanghai Medical & Pharmaceutical Journal
关键词
化痰祛瘀汤
急性脑梗死
神经功能
生活能力
Huatan Quyu decoction
acute cerebral infarction
nerve function
living ability
