摘要
目的探究毓麟珠汤加减治疗肾阴虚型卵巢储备不足的临床疗效。方法选取2019年1月至2020年1月于榆林市中医医院就诊的120例肾阴虚型卵巢储备不足患者作为研究对象,按照随机数字表法分为观察组(n=60)和对照组(n=60)。观察组采用毓麟珠汤加减治疗,对照组采用坤泰胶囊治疗。对比两组的治疗总有效率、中医症状积分、血清性激素指标改善情况及阴道超声检查指标。结果观察组和对照组的治疗总有效率分别为95.00%、80.00%,差异具有统计学意义(P<0.05);治疗后,观察组患者的雌二醇(E_(2))[(94.20±3.76)pg/mL]、卵泡刺激素(FSH)[(8.50±1.33)IU/L]及血清抗苗勒管激素(AMH)[(1.23±0.25)μg/L]水平显著高于对照组[(79.32±2.98)pg/mL、(6.50±1.21)IU/L、(0.81±0.19)μg/L],观察组患者的FSH/黄体生成素(LH)(0.88±0.12)显著低于对照组(1.20±0.19),差异具有统计学意义(P<0.05);治疗后,观察组患者的中医症状积分[(4.65±0.25)分]显著低于对照组[(7.02±0.26)分],差异具有统计学意义(P<0.05);治疗后,观察组患者的左卵巢体积[(3.60±0.40)cm^(3)]、右卵巢体积[(3.14±0.26)cm^(3)]、子宫内膜厚度[(0.47±0.16)cm]、子宫体积[(23.90±3.00)cm^(3)]显著高于对照组[(3.29±0.34)cm^(3)、(3.00±0.24)cm^(3)、(0.40±0.12)cm、(22.02±2.42)cm^(3)],差异具有统计学意义(P<0.05)。结论毓麟珠汤加减治疗肾阴虚型卵巢储备不足可显著提高患者的临床治疗效果,有效调控患者的血清性激素指标,显著改善患者的临床症状。
Objective To explore the clinical efficacy of Yulinzhu Decoction in the treatment of ovarian reserve deficiency with kidney-yin deficiency.Methods 120 patients with ovarian reserve deficiency with kidney-yin deficiency treated in Yulin Hospital of Traditional Chinese Medicine from January 2019 to January 2020 were selected as the research objects.According to the random number table method,they were divided into observation group(n=60)and control group(n=60).The observation group was treated with Yulinzhu Decoction,and the control group was treated with Kuntai Capsule.The total effective rate,traditional Chinese medicine(TCM)symptom score,serum sex hormone index improvement and vaginal ultrasonography index were compared between the two groups.Results After treatment,the total effective rate of the observation group and the control group was 95.00%and 80.00%,respectively,with statistical significance(P<0.05).The levels of estradiol(E_(2))[(94.20±3.76)pg/mL],follicle stimulating hormone(FSH)[(8.50±1.33)IU/L]and serum anti-Müllerian hormone(AMH)[(1.23±0.25)μg/L]in observation group were significantly higher than those in control group[(79.32±2.98)pg/mL,(6.50±1.21)IU/L and(0.81±0.19)μg/L]after treatment,the difference was statistically significant(P<0.05).The FSH/luteinizing hormone(LH)level in observation group(0.88±0.12)was significantly lower than that in control group(1.20±0.19)after treatment,and the difference was statistically significant(P<0.05).The TCM symptom score of observation group[(4.65±0.25)points]was significantly lower than that of control group[(7.02±0.26)points]after treatment,and the difference was statistically significant(P<0.05).The left ovarian volume[(3.60±0.40)cm^(3)],right ovarian volume[(3.14±0.26)cm^(3)],uterine endometrial thickness[(0.47±0.16)cm]and uterine volume[(23.90±3.00)cm^(3)]in observation group were significantly higher than those in control group[(3.29±0.34)cm^(3),(3.00±0.24)cm^(3),(0.40±0.12)cm,(22.02±2.42)cm^(3)]after treatment,the differences were sta
作者
艾贝贝
窦娜
AI Beibei;DOU Na(Department of Gynecology,Yulin Hospital ofTraditional Chinese Medicine,Yulin 719000,Shaanxi,China)
出处
《中国性科学》
2022年第3期133-136,共4页
Chinese Journal of Human Sexuality
关键词
毓麟珠汤加减
肾阴虚型卵巢储备不足
临床分析
Yulinzhu Decoction
Ovarian reserve deficiency with kidney-yin deficiency
Clinical analysis
