摘要
为了实现对恶性肿瘤的早期诊断,提高治疗效果,改善患者临床症状,综述了CDC20在常见恶性肿瘤中的表达及临床意义。研究表明,在各种类型的人类癌症中,CDC20的高表达与临床病理参数相关,且CDC20的异常表达与多种肿瘤的预后不良有关,因此开发特异的CDC20抑制剂可能是改善人类癌症治疗的一种策略,为恶性肿瘤的早期诊疗、疗效评估及预后判断提供了新的方向。
In order to achieve the early diagnosis of malignant tumor,improve treatment effect,and improve patient’s clinical symptoms,the study summarizes the expression of CDC20 in malignant tumor and it clinical significance.The study show that,in various kinds of human cancers,high expression of CDC20 is related with clinicopathological parameter,and the abnormal expression of CDC20 is related with the adverse prognosis of various tumors.Therefore the development of specific CDC20 inhibitor may become a strategy for improving human cancer treatment,and provides the new orientation for the early diagnosis,curative effect evaluation and prognosis judgement.
作者
叶蕾
Ye Lei(Xiangtan Medicine & Health Vocational College, Xiangtan 411104, China)
出处
《黑龙江科学》
2022年第6期134-136,共3页
Heilongjiang Science
基金
2018年度湘潭医卫职业技术学院自科一般课题“CDC20在脊索瘤复发中的作用研究”(ZRKX2018-006)。
