摘要
脓毒症是机体对感染的反应失调而导致危及生命的器官功能障碍,是严重威胁人类健康的重大疾病之一。2021年10月发布的《拯救脓毒症运动:脓毒症与感染性休克治疗国际指南2021版》,涵盖筛查与早期治疗、感染、血流动力学管理、机械通气、支持治疗以及远期结局与照护目标等6大部分,共计93个条目。本文对该指南内容予以解读,并对相关争议予以梳理分析。该指南为脓毒症诊疗提供了较准确的方向和框架,也可能提供了一个督促全球脓毒症领域研究者深入开展个体化研究的契机。
Sepsis is defined as life-threatening organ dysfunction secondary to a dysregulated host response to infection.It is considered a major cause of death and health loss worldwide.Surviving Sepsis Campaign:International Guidelines for Management of Sepsis and Septic Shock 2021,released in October 2021,included 93 total statements,which addressed screening and initial resuscitation,infection,hemodynamics,ventilation,additional therapies,and goals of care and long-term outcomes.This review interpreted the content ofthe guidelines and also analyzed the underlying issues.The guidelines provide a more accurate framework and guidance for the diagnosis and treatment of sepsis,and may also provide an opportunity to urge researchers in the field of sepsis worldwide to implement further individualized research.
作者
纪文焘
孟岩
薄禄龙
万小健
邓小明
Ji Wentao;Meng Yan;Bo Lulong;Wan Xiaojian;Deng Xiaoming(Faculty of Anesthesiology,Changhai Hospital,Naval Medical University,Shanghai 200433,China)
出处
《中华麻醉学杂志》
CAS
CSCD
北大核心
2021年第12期1409-1413,共5页
Chinese Journal of Anesthesiology
基金
上海市青年科技启明星计划(19QA1408500)
海军军医大学附属长海医院"234学科攀峰计划"(2020YXK053)。
